Sosa Belaustegui Agustina, Flagel Santiago, Frydman Ana, Labato Mariana, Myburg Cristina, Risso Jorge
V Cátedra de Medicina, Servicio de Internación, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina. E-mail:
Medicina (B Aires). 2014;74(2):130-2.
Immune reconstitution syndrome is a set of acute inflammatory phenomena that occur as a result of restored immunity generating a paradoxical worsening of a prior infection or an inflammatory process. This syndrome occurs in human immunodeficiency virus infected patients after starting antiretroviral treatment. The most frequent associated infections are those produced by mycobacteria, herpes, cryptococcosis, hepatitis B, cytomegalovirus, Pneumocystis jirovecii and worsening of progressive multifocal leukoencephalopathy secondary to JC virus. We present the case of a patient with human immunodeficiency virus who developed the immune reconstitution syndrome secondary to Pneumocystis jirovecii.
免疫重建综合征是一组急性炎症现象,它是由于恢复的免疫力导致先前感染或炎症过程出现矛盾性恶化而发生的。这种综合征发生在开始抗逆转录病毒治疗后的人类免疫缺陷病毒感染患者中。最常见的相关感染是由分枝杆菌、疱疹、隐球菌病、乙型肝炎、巨细胞病毒、耶氏肺孢子菌引起的感染,以及继发于JC病毒的进行性多灶性白质脑病的恶化。我们报告一例人类免疫缺陷病毒患者继发耶氏肺孢子菌感染后发生免疫重建综合征的病例。