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类风湿关节炎相关间质性肺疾病:综述

Rheumatoid arthritis associated interstitial lung disease: a review.

作者信息

Assayag Deborah, Lee Joyce S, King Talmadge E

机构信息

Division of Pulmonary, Critical Care, Allergy and Sleep Medicine; Department of Medicine, University of California San Francisco (UCSF), San Francisco, CA, USA. E-mail:

出版信息

Medicina (B Aires). 2014;74(2):158-65.

Abstract

Rheumatoid arthritis is a common inflammatory disease affecting about 1% of the population. Interstitial lung disease is a serious and frequent complication of rheumatoid arthritis. Rheumatoid arthritis associated interstitial lung disease (RA-ILD) is characterized by several histopathologic subtypes. This article reviews the proposed pathogenesis and risk factors for RA-ILD. We also outline the important steps involved in the work-up of RA-ILD and review the evidence for treatment and prognosis.

摘要

类风湿关节炎是一种常见的炎症性疾病,影响着约1%的人口。间质性肺疾病是类风湿关节炎严重且常见的并发症。类风湿关节炎相关间质性肺疾病(RA-ILD)具有多种组织病理学亚型。本文综述了RA-ILD的发病机制及危险因素。我们还概述了RA-ILD检查的重要步骤,并综述了其治疗及预后的相关证据。

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