Centre for Plant Health, Sidney Laboratory, Canadian Food Inspection Agency, 8801 East Saanich Road, North Saanich, BC, V8L 1H3, Canada,
Arch Virol. 2014 Sep;159(9):2463-8. doi: 10.1007/s00705-014-2075-6. Epub 2014 Apr 16.
The genome of a virus associated with cherry twisted leaf disease (CTLaV, isolate ZH) was sequenced and consists of 8431 nucleotides, excluding a poly(A) tail at the 3' end. Genome analysis shows that CTLaV-ZH represents a new and distinct species and has a genome organization similar to those of unassigned viruses in the family Betaflexiviridae. The CTLaV-ZH genome has five open reading frames (ORFs), with putative ORFs within ORF2 and ORF5, identified as ORF2a and ORF5a, respectively. The AUG start codons of ORF2a and ORF5a are in contexts suitable for efficient translation, with appropriate stop codons in frame.
与樱桃卷叶病相关的病毒（CTLaV，分离株 ZH）的基因组已被测序，其大小为 8431 个核苷酸，不包括 3'端的 poly(A)尾。基因组分析表明，CTLaV-ZH 代表了一个新的独特物种，其基因组结构与贝塔病毒科中未分类的病毒相似。CTLaV-ZH 基因组有五个开放阅读框（ORFs），ORF2 和 ORF5 内的推定 ORFs 分别被鉴定为 ORF2a 和 ORF5a。ORF2a 和 ORF5a 的 AUG 起始密码子处于有利于高效翻译的环境中，具有适当的框内终止密码子。
