伊朗一家三级眼科护理中心葡萄膜炎的临床模式
Clinical Patterns of Uveitis in an Iranian Tertiary Eye-care Center.
作者信息
Kianersi Farzan, Mohammadi Zahra, Ghanbari Heshmatollah, Ghoreyshi Seyed Mohammad, Karimzadeh Hadi, Soheilian Masoud
机构信息
a Department of Ophthalmology , School of Medicine, Isfahan University of Medical Science , Isfahan , Iran.
b Isfahan Eye Research Center, Feiz Eye Hospital, Isfahan University of Medical Sciences , Isfahan , Iran.
出版信息
Ocul Immunol Inflamm. 2015 Aug;23(4):278-282. doi: 10.3109/09273948.2014.902474. Epub 2014 Apr 16.
PURPOSE
This study aimed to analyze the clinical patterns and etiology of uveitis in Isfahan, Iran.
METHODS
In this descriptive research, the records of 2016 patients with uveitis referred to a tertiary eye care centers were examined. Age, sex, clinical and anatomical features, and etiology of disease were recorded and analyzed.
RESULTS
The mean age of onset of uveitis was 33.76 years and the women/men ratio was 1.2/1.0. Anterior uveitis was the most common (42.9%) type followed by posterior (21.4%), intermediate (19.3%), and pan uveitis (16.31%). Noninfectious causes had more roles (76.5%) in the etiology of uveitis. A total of 43.9% of the patients had unknown etiology (idiopathic). The most common known etiologies were toxoplasmosis, Behçet disease and Fuchs heterochromic iridiocyclitis (FHI), respectively. In 15.6%, there was an underlying systemic disease.
CONCLUSION
There were some differences in the clinical and etiologic pattern of uveitis in Isfahan. Environmental, genetic, and geographical factors may contribute to this difference.
目的
本研究旨在分析伊朗伊斯法罕葡萄膜炎的临床模式及病因。
方法
在这项描述性研究中，对转诊至三级眼科护理中心的2016例葡萄膜炎患者的记录进行了检查。记录并分析患者的年龄、性别、临床和解剖特征以及疾病病因。
结果
葡萄膜炎的平均发病年龄为33.76岁，女性/男性比例为1.2/1.0。前葡萄膜炎是最常见的类型（42.9%），其次是后葡萄膜炎（21.4%）、中间葡萄膜炎（19.3%）和全葡萄膜炎（16.31%）。非感染性病因在葡萄膜炎病因中占比更大（76.5%）。共有43.9%的患者病因不明（特发性）。最常见的已知病因分别是弓形虫病、白塞病和富克斯异色性虹膜睫状体炎（FHI）。15.6%的患者存在潜在的全身性疾病。
结论
伊斯法罕葡萄膜炎的临床和病因模式存在一些差异。环境、遗传和地理因素可能导致了这种差异。
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