Bagheri Masood, Ahoor Mohammad-Hosein, Jafari Ahad, Hashemi Hesam Sadat, Mohammadkhani Mehdi
Department of Ophthalmology, Imam Khomeini Eye Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Department of Ophthalmology, Nikookari Eye Center, Tabriz University of Medical Sciences, Tabriz, Iran.
J Ophthalmic Vis Res. 2021 Jan 20;16(1):93-102. doi: 10.18502/jovr.v16i1.8255. eCollection 2021 Jan-Mar.
Uveitis is the third leading cause of blindness worldwide. This study aimed to summarize the pattern of uveitis in Iran through a systematic review.
This review was conducted according to the guidelines for systematic reviews in the following four steps: literature search, study selection and assessment, inclusion and exclusion criteria, and statistical analysis.
One hundred and fifteen articles were identified by an encyclopedic literature search, and three independent investigators examined them according to the defined inclusion and exclusion criteria. Eventually, 109 manuscripts were retrieved and six cross-sectional studies covering 3,567 patients were included and reviewed. According to the results, the mean age of patients was 40 years, and sex was not a statistically significant predisposing factor. The most common anatomical pattern of involvement was anterior uveitis, and the prevalence of the other three types of uveitis, including middle, posterior, and pan-uveitis, were almost equal. Overall, the most common etiologies of uveitis in the Iranian population were idiopathic uveitis, toxoplasmosis, Behcet's syndrome, and Fuchs heterochromic iridocyclitis.
This study depicted the pattern of uveitis in the Iranian society; this can help physicians in the diagnostic approach, management, and treatment of patients.
葡萄膜炎是全球第三大致盲原因。本研究旨在通过系统评价总结伊朗葡萄膜炎的发病模式。
本评价按照系统评价指南分以下四个步骤进行：文献检索、研究选择与评估、纳入与排除标准以及统计分析。
通过全面的文献检索确定了115篇文章，由三名独立研究人员根据既定的纳入和排除标准对其进行审查。最终，检索到109篇手稿，纳入并审查了6项横断面研究，涵盖3567例患者。根据结果，患者的平均年龄为40岁，性别不是具有统计学意义的易感因素。最常见的受累解剖模式是前葡萄膜炎，其他三种葡萄膜炎类型（包括中间葡萄膜炎、后葡萄膜炎和全葡萄膜炎）的患病率几乎相等。总体而言，伊朗人群中葡萄膜炎最常见的病因是特发性葡萄膜炎、弓形虫病、白塞病和富克斯异色性虹膜睫状体炎。
本研究描绘了伊朗社会葡萄膜炎的发病模式；这有助于医生对患者进行诊断、管理和治疗。
