Fuchs 葡萄膜炎综合征的视网膜和脉络膜厚度：对侧眼研究。
Retinal and choroidal thickness in fuchs uveitis syndrome: a contralateral eye study.
机构信息
Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran.
出版信息
BMC Ophthalmol. 2024 Jul 12;24(1):283. doi: 10.1186/s12886-024-03554-y.
BACKGROUND
To investigate the subfoveal retinal and choroidal thickness in patients with unilateral Fuchs Uveitis Syndrome (FUS).
METHODS
This comparative contralateral study was performed in affected eyes with FUS versus fellow eyes. For each eye parameters such as subfoveal choroidal thickness (SCT), subfoveal choriocapillary thickness (SCCT), central macular thickness (CMT), and central macular volume (CMV) were measured; then the measured values of affected and fellow unaffected eye were compared.
RESULTS
Thirty-seven patients (74 eyes) including 19 females (51.4%) with a mean age of 36.9 ± 7.6 years were enrolled. The mean SCT was lower in the affected eyes (344.51 ± 91.67) than in the fellow (375.59 ± 87.33) with adjusting for duration of disease and axial lengths (P < 0.001). The mean SCCT, CMT, and CMV were higher in eyes with FUS than in fellow eyes (P < 0.05).
CONCLUSIONS
The result of our study demonstrated that affected eyes in patients with FUS tend to have thinner SCT and thicker SCCT and CMT compared to uninvolved fellow eyes.
背景
研究单侧 Fuchs 葡萄膜炎综合征（FUS）患者的中心凹下视网膜和脉络膜厚度。
方法
本研究为对照性的对侧研究，纳入了单侧 FUS 患者的患眼和对侧眼。对每只眼的参数进行测量，如中心凹下脉络膜厚度（SCT）、中心凹下毛细血管厚度（SCCT）、中心黄斑厚度（CMT）和中心黄斑体积（CMV）；然后比较患眼和对侧未受影响眼的测量值。
结果
共纳入 37 名患者（74 只眼），其中女性 19 名（51.4%），平均年龄 36.9±7.6 岁。调整疾病持续时间和眼轴长度后，患眼的平均 SCT（344.51±91.67）低于对侧眼（375.59±87.33）（P<0.001）。患眼的平均 SCCT、CMT 和 CMV 高于对侧眼（P<0.05）。
结论
本研究结果表明，与对侧未受累眼相比，FUS 患者的患眼 SCT 较薄，SCCT 和 CMT 较厚。
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