频繁复发的生殖器疱疹的抑制作用：阿昔洛韦与异丙肌苷比较
Suppression of frequently recurring genital herpes: acyclovir v inosine pranobex.
作者信息
Mindel A, Carney O, Sonnex C, Freris M, Patou G, Williams P
机构信息
Academic Department of Genitourinary Medicine, University College and Middlesex School of Medicine, London.
出版信息
Genitourin Med. 1989 Apr;65(2):103-5. doi: 10.1136/sti.65.2.103.
Abstract
The suppressive action of acyclovir and inosine pranobex was compared in a randomised double blind controlled trial in patients with frequently recurring genital herpes. Fourteen patients received acyclovir and 17 inosine pranobex. Treatment continued for 12 weeks. The time to the first recurrence was significantly longer and the frequency of recurrences significantly less in the recipients of acyclovir. No important side effects were noted. It is concluded that acyclovir is the treatment of choice to suppress often recurring genital herpes.
摘要
在一项针对复发性生殖器疱疹患者的随机双盲对照试验中，比较了阿昔洛韦和异丙肌苷的抑制作用。14名患者接受阿昔洛韦治疗，17名患者接受异丙肌苷治疗。治疗持续12周。阿昔洛韦治疗组患者首次复发的时间明显延长，复发频率明显降低。未观察到严重的副作用。结论是，阿昔洛韦是抑制复发性生殖器疱疹的首选治疗药物。
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本文引用的文献
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Genital herpes: hype or hope?生殖器疱疹：炒作还是希望？
Br Med J (Clin Res Ed). 1983 Jun 4;286(6380):1767-8. doi: 10.1136/bmj.286.6380.1767.
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Suppression of frequently recurring genital herpes. A placebo-controlled double-blind trial of oral acyclovir.复发性生殖器疱疹的抑制作用。口服阿昔洛韦的安慰剂对照双盲试验。
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Acyclovir prophylaxis of recurrent genital herpes: randomised placebo controlled crossover study.阿昔洛韦预防复发性生殖器疱疹：随机安慰剂对照交叉研究。
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