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复发性生殖器疱疹:男性和女性的临床及病毒学特征

Recurrent genital herpes: clinical and virological features in men and women.

作者信息

Mindel A, Coker D M, Faherty A, Williams P

机构信息

Academic Department of Genitourinary Medicine, Middlesex Hospital Medical School, London.

出版信息

Genitourin Med. 1988 Apr;64(2):103-6. doi: 10.1136/sti.64.2.103.

DOI:10.1136/sti.64.2.103
PMID:3384426
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1194166/
Abstract

One hundred and forty eight patients (69 women and 79 men) with often recurring genital herpes were observed for two months. Men had 119 observed recurrences and women 104. The attacks were significantly longer in men than women (8.7 days v 6.6 days, p = 0.005). Significantly more women complained of symptoms, however, and when symptoms occurred they were more severe. Other significant differences between men and women included age (men were older than women); more men had previously had sexually transmitted diseases; more men had infected a sexual partner, but fewer knew the source of their infection; and men had more lesions at each attack. Positive viral culture results were shown to depend on the amount of erythema, the number of lesions, and the presence of vesicles.

摘要

对148例(69名女性和79名男性)复发性生殖器疱疹患者进行了为期两个月的观察。男性观察到119次复发,女性观察到104次复发。男性的发作时间明显长于女性(8.7天对6.6天,p = 0.005)。然而,抱怨有症状的女性明显更多,而且症状出现时更严重。男性和女性之间的其他显著差异包括年龄(男性比女性年龄大);更多男性曾患过性传播疾病;更多男性感染过性伴侣,但较少有人知道感染源;男性每次发作时的皮损更多。病毒培养阳性结果显示取决于红斑量、皮损数量和水疱的存在情况。

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本文引用的文献

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Coping and adjustment to genital herpes.
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Genital herpes simplex virus infections: clinical manifestations, course, and complications.生殖器单纯疱疹病毒感染:临床表现、病程及并发症
Ann Intern Med. 1983 Jun;98(6):958-72. doi: 10.7326/0003-4819-98-6-958.
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The course of untreated recurrent genital herpes simplex infection in 27 women.27名女性未经治疗的复发性单纯疱疹病毒生殖器感染病程
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Clinical features of herpes genitalis.生殖器疱疹的临床特征。
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Psychological aspects of recurrences of genital herpes.生殖器疱疹复发的心理学方面
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Frequency of acquisition of first-episode genital infection with herpes simplex virus from symptomatic and asymptomatic source contacts.从有症状和无症状传染源接触者处首次感染单纯疱疹病毒引起生殖器感染的频率。
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Prevalence of antibodies to human immunodeficiency virus, gonorrhoea rates, and changed sexual behaviour in homosexual men in London.伦敦男同性恋者中人类免疫缺陷病毒抗体的流行率、淋病发病率及性行为变化
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Clinical and virologic course of herpes simplex genitalis.单纯疱疹性生殖器炎的临床及病毒学病程
West J Med. 1979 May;130(5):414-21.