In vitro pemphigus vulgaris model using organotypic cultures of human epidermal keratinocytes.
作者信息
Hunziker T, Boillat C, Gerber H A, Wiesmann U, Wintroub B U
机构信息
Department of Dermatology, University of Berne, Switzerland.
出版信息
J Invest Dermatol. 1989 Aug;93(2):263-7. doi: 10.1111/1523-1747.ep12277586.
PMID:2474033
Abstract
Using the Combi-ring-dish (CRD), a new culture device, organotypic cultures of human epidermal keratinocytes were grown on bovine eye lens capsules. In these highly differentiated cultures, typical suprabasal acantholysis was induced by pemphigus vulgaris antibodies. This in vitro pemphigus vulgaris model may be used to analyse keratinocyte-derived factors causing acantholysis in experimental pemphigus.
摘要
相似文献
1
In vitro pemphigus vulgaris model using organotypic cultures of human epidermal keratinocytes.
J Invest Dermatol. 1989 Aug;93(2):263-7. doi: 10.1111/1523-1747.ep12277586.
2
The ultrastructure of acantholysis in pemphigus vulgaris.寻常型天疱疮棘层松解的超微结构
Br J Dermatol. 2009 Feb;160(2):460-1. doi: 10.1111/j.1365-2133.2008.08971.x. Epub 2008 Dec 11.
3
In vivo binding site of pemphigus vulgaris antibodies and their fate during acantholysis.
J Am Acad Dermatol. 1989 Apr;20(4):578-82. doi: 10.1016/s0190-9622(89)70066-9.
4
Role of plasminogen activator in pemphigus vulgaris.纤溶酶原激活剂在寻常型天疱疮中的作用。
Am J Pathol. 1989 Mar;134(3):561-9.
5
Locations of acantholysis in pemphigus vulgaris and pemphigus foliaceus.寻常型天疱疮和落叶型天疱疮棘层松解的部位。
J Cutan Pathol. 2014 Nov;41(11):880-9. doi: 10.1111/cup.12384. Epub 2014 Nov 3.
6
An organ culture model for the study of pemphigus acantholysis.一种用于研究天疱疮棘层松解的器官培养模型。
Br J Dermatol. 1977 Mar;96(3):295-302. doi: 10.1111/j.1365-2133.1977.tb06141.x.
7
Apoptotic mechanism in pemphigus autoimmunoglobulins-induced acantholysis--possible involvement of the EGF receptor.天疱疮自身免疫球蛋白诱导棘层松解中的凋亡机制——表皮生长因子受体的可能参与
Autoimmunity. 2006 Nov;39(7):563-75. doi: 10.1080/08916930600971836.
8
Proteinase activation: a mechanism for cellular dyshesion in pemphigus.蛋白酶激活：天疱疮中细胞黏附障碍的一种机制。
J Invest Dermatol. 1980 May;74(5):363-7. doi: 10.1111/1523-1747.ep12543780.
9
In vitro acantholysis induced by D-penicillamine, captopril, and piroxicam on dead de-epidermized dermis.青霉胺、卡托普利和吡罗昔康在死亡的去表皮真皮上诱导的体外棘层松解。
J Cutan Pathol. 1992 Jun;19(3):181-6. doi: 10.1111/j.1600-0560.1992.tb01656.x.
10
Synergistic actions of pemphigus vulgaris IgG, Fas-ligand and tumor necrosis factor-alpha during induction of basal cell shrinkage and acantholysis.寻常型天疱疮IgG、Fas配体和肿瘤坏死因子-α在诱导基底细胞收缩和棘层松解过程中的协同作用。
Autoimmunity. 2006 Nov;39(7):557-62. doi: 10.1080/08916930600971729.
引用本文的文献
1
Experimental human cell and tissue models of pemphigus.天疱疮的实验性人体细胞和组织模型。
Dermatol Res Pract. 2010;2010:143871. doi: 10.1155/2010/143871. Epub 2010 May 26.
2
Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes.当在基质胶内培养时，外根鞘（ORS）细胞会组织形成表皮样囊肿样球体：人ORS细胞与毛囊间角质形成细胞的光学显微镜和免疫组织学比较。
Cell Tissue Res. 1994 Jan;275(1):169-76. doi: 10.1007/BF00305384.
Zotero 插件