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小肠克罗恩病中的胶囊内镜检查

Capsule endoscopy in the small bowel Crohn's disease.

作者信息

Argüelles-Arias Federico, Rodríguez-Oballe Juan, Duarte-Chang Calixto, Castro-Laria Luisa, García-Montes Josefa María, Caunedo-Álvarez Angel, Herrerías-Gutiérrez Juan Manuel

机构信息

Clinical Unit of Gastroenterology, University Hospital Virgen Macarena, Seville, Spain.

出版信息

Gastroenterol Res Pract. 2014;2014:529136. doi: 10.1155/2014/529136. Epub 2014 Mar 11.

Abstract

CD is a chronic inflammatory disorder associated to mucosal and transmural inflammation of the bowel wall. It is well known that CD can affect the entire gastrointestinal. Therefore, ileocolonoscopy and biopsies of the terminal ileum as well as of each colonic segment to look for microscopic evidence of CD are the first-line procedures to establish the diagnosis. However, it has been observed that up to 30% of the patients have only small bowel involvement. Evaluation of the small bowel has been made with radiological procedures, barium radiography, and abdominal computed tomography or by ileocolonoscopy or enteroscopy, but they have many recognized limitations. CE is undoubtedly a very useful diagnostic tool proposed to observe small-bowel lesions undetectable by conventional endoscopy or radiologic studies. We review different studies that have been published reporting the use of CE in suspected and evaluation of the extension or the recurrence in CD and also its use in pediatric population and its complications.

摘要

克罗恩病是一种与肠壁黏膜和透壁性炎症相关的慢性炎症性疾病。众所周知,克罗恩病可累及整个胃肠道。因此,进行回结肠镜检查以及取末端回肠和各结肠段的活检以寻找克罗恩病的微观证据,是确立诊断的一线检查方法。然而,据观察,高达30%的患者仅累及小肠。小肠评估已通过放射学检查、钡剂造影、腹部计算机断层扫描或通过回结肠镜检查或小肠镜检查来进行,但这些检查有许多公认的局限性。胶囊内镜无疑是一种非常有用的诊断工具,用于观察常规内镜检查或放射学检查无法发现的小肠病变。我们回顾了已发表的不同研究,这些研究报告了胶囊内镜在疑似克罗恩病、评估其病变范围或复发情况中的应用,以及其在儿科患者中的应用及其并发症。

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本文引用的文献

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Capsule endoscopy is superior to small-bowel follow-through and equivalent to ileocolonoscopy in suspected Crohn's disease.
Clin Gastroenterol Hepatol. 2014 Apr;12(4):609-15. doi: 10.1016/j.cgh.2013.09.028. Epub 2013 Sep 27.
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