Caffier G, Shvinka N E
Central Inst. Occupat. Med., Dept. Work Physiol, Berlin, GDR.
Biomed Biochim Acta. 1989;48(5-6):S552-7.
Gramicidin A, amphotericin B and nystatin increased the cation conductance and efflux rates from frog skeletal muscle fibres. Concerning gramicidin A, the characteristics tested are similar to those reported for BLM. Therefore, a channel formation like that in BLM is assumed for the muscle cell membrane. On the other hand, the kinetics of channel formation are different in muscle membrane and BLM. This suggests that the processes which limit the rate of channel formation are different.
短杆菌肽A、两性霉素B和制霉菌素增加了蛙骨骼肌纤维的阳离子电导率和外流速率。关于短杆菌肽A,所测试的特性与报道的黑脂质膜(BLM)的特性相似。因此,假定肌肉细胞膜中形成的通道与BLM中的类似。另一方面,肌肉膜和BLM中通道形成的动力学不同。这表明限制通道形成速率的过程是不同的。