Nishio Shoji, Fukunishi Shigeo, Juichi Miura, Sahoko Koyanagi, Fujihara Yuki, Fukui Tomokazu, Yoshiya Shinichi
Department of Orthopedic Surgery, Hyogo College of Medicine , Japan.
Departments of Orthopedic Surgery and Anesthesia, Hyogo Prefectural Tsukaguchi Hospital , Japan.
Orthop Rev (Pavia). 2014 Mar 12;6(1):5138. doi: 10.4081/or.2014.5138. eCollection 2014 Jan 20.
Thirty-six patients who underwent primary unilateral total hip arthroplasty (THA) were randomly allocated to 4 groups with different pain control protocols; continuous femoral nerve block (FNB group), single-shot caudal epidural block with morphine (EB group), intravenous patient-controlled analgesia with fentanyl (IV-PCA group), and systemic administration of nonsteroidal anti-inflammatory drugs (NSAIDs group). Postoperative pain was assessed using the numerical rating scale (NRS) scores and the analgesic effect was compared among the groups. The NRS upon arrival at the recovery room and 6 hours after surgery in the FNB, EB, and IV-PCA groups were significantly lower than that in the NSAIDs group. The amount of additional analgesics requested by the patient was smaller in the FNB, EB, and IV-PCA groups as compared to the NSAIDs group. Regarding the complications related to the analgesia, 5 of the 9 patients in the IV-PCA group complained nausea and vomiting and received antiemetic drugs. Delay in the rehabilitation process due to drowsiness was encountered in 3 patients in this group, while no patient in the FNB and EB groups suffered from delayed rehabilitation. Considering both the analgesic effect and the potential risk of complications, continuous femoral nerve blocks and caudal epidural blocks for are recommended for postoperative pain control after THA procedure.
三十六例行初次单侧全髋关节置换术(THA)的患者被随机分为4组,采用不同的疼痛控制方案;连续股神经阻滞(FNB组)、单次尾段硬膜外注射吗啡(EB组)、静脉自控镇痛泵输注芬太尼(IV-PCA组)以及全身应用非甾体类抗炎药(NSAIDs组)。采用数字评分量表(NRS)评分评估术后疼痛,并比较各组的镇痛效果。FNB组、EB组和IV-PCA组患者到达恢复室时及术后6小时的NRS评分显著低于NSAIDs组。与NSAIDs组相比,FNB组、EB组和IV-PCA组患者要求追加的镇痛药用量更少。关于镇痛相关并发症,IV-PCA组9例患者中有5例出现恶心呕吐并接受了止吐药物治疗。该组有3例患者因嗜睡导致康复进程延迟,而FNB组和EB组均无患者出现康复延迟。综合考虑镇痛效果和潜在并发症风险,推荐在THA术后采用连续股神经阻滞和尾段硬膜外阻滞进行疼痛控制。