后部可逆性脑病综合征：妊娠患者与非妊娠患者的差异
Posterior reversible encephalopathy syndrome: differences between pregnant and non-pregnant patients.
作者信息
Marrone Luiz Carlos Porcello, Gadonski Giovani, Diogo Luciano Passamani, Brunelli João Pedro Farina, Martins William Alves, Laguna Gabriela de Oliveira, Bahlis Laura Fuchs, Filho João Rubião Hoefel, da Costa Bartira Ercilia Pinheiro, Poli-de-Figueiredo Carlos Eduardo, Marrone Antônio Carlos Huf, da Costa Jaderson Costa
机构信息
Service of Neurology, Instituto do Cérebro, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul , Porto Alegre, Brazil.
Service of Nephrology, Instituto do Cérebro, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul , Porto Alegre, Brazil.
出版信息
Neurol Int. 2014 Mar 24;6(1):5376. doi: 10.4081/ni.2014.5376. eCollection 2014 Jan 17.
Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiologic entity not yet understood, that presents with transient neurologic symptoms and particular radiological findings. Few papers show the differences between pregnant and non-pregnant patients. We review the cases of 38 women diagnosed with PRES, in order to find significant differences between pregnant (18) and non-pregnant (20) patients. We found differences among the age of patients (25.83 years old in pregnant and 29.31 years old in non pregnant; P=0.001); in the mean of highest systolic blood pressure, that was higher in non-pregnant group (185:162 mmHg; P=0.121); and in creatinine levels that was higher in non-pregnant group (3.47:1.04 mg/dL; P=0.001). To our knowledge, just a few papers analyzed whether PRES syndrome presented in the same way in pregnant and non-pregnant patients. The differences and the possible pathophisiology of this syndrome still remain enigmatic.
后部可逆性脑病综合征（PRES）是一种尚未被完全理解的临床-放射学实体，表现为短暂的神经系统症状和特定的影像学表现。很少有文献显示孕妇和非孕妇患者之间的差异。我们回顾了38例被诊断为PRES的女性病例，以找出孕妇（18例）和非孕妇（20例）患者之间的显著差异。我们发现患者年龄存在差异（孕妇为25.83岁，非孕妇为29.31岁；P=0.001）；最高收缩压平均值也有差异，非孕妇组更高（185:162 mmHg；P=0.121）；肌酐水平同样存在差异，非孕妇组更高（3.47:1.04 mg/dL；P=0.001）。据我们所知，仅有少数文献分析了PRES综合征在孕妇和非孕妇患者中的表现是否相同。该综合征的差异及可能的病理生理学机制仍然不明。
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