与FOLFOX化疗相关的后部可逆性脑病综合征
Posterior Reversible Encephalopathy Syndrome Associated with FOLFOX Chemotherapy.
作者信息
Porcello Marrone Luiz Carlos, Marrone Bianca Fontana, Pascoal Tharick Ali, Schilling Lucas Porcello, Soder Ricardo Bernardi, Ferreira Sheila Schuch, Gadonski Giovani, da Costa Jaderson Costa
机构信息
Hospital São Lucas/Instituto do Cérebro (Inscer), Pontificia Universidade Católica do Rio Grande do Sul (PUCRS), Avenida Ipiranga 6690, 90610-000 Porto Alegre, RS, Brazil.
出版信息
Case Rep Oncol Med. 2013;2013:306983. doi: 10.1155/2013/306983. Epub 2013 Feb 27.
Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiologic entity characterized by headaches, altered mental status, seizures, visual loss, and characteristic imaging pattern in brain MRI. The cause of PRES is not yet understood. We report a case of a 27-year-old woman that developed PRES after the use of FOLFOX 5 (oxaliplatin/5-Fluoracil/Leucovorin) chemotherapy for a colorectal cancer.
后部可逆性脑病综合征（PRES）是一种临床放射学疾病，其特征为头痛、精神状态改变、癫痫发作、视力丧失以及脑部磁共振成像（MRI）的特征性影像学表现。PRES的病因尚不清楚。我们报告一例27岁女性病例，该患者在使用FOLFOX 5（奥沙利铂/5-氟尿嘧啶/亚叶酸钙）化疗治疗结直肠癌后发生了PRES。
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