Tomczyk Mateusz, Nowak Witold, Jaźwa Agnieszka
Postepy Biochem. 2013;59(4):357-64.
Vascular endothelium is the layer of cells that line blood vessels and serve as the primary barrier between the blood and the tissues. These cells play many important functions such as regulation of the vascular tone, blood flow and pressure control, maintaining the balance between thrombosis and fibrinolysis, participation in immune system reactions and new blood vessels formation. Disturbance in any of these functions may contribute to the development of different diseases such as for e.g. hypertension, atherosclerosis and deep vein thrombosis, as well as cancer.
血管内皮是一层衬于血管内表面的细胞,是血液与组织之间的主要屏障。这些细胞发挥着许多重要功能,如调节血管张力、控制血流和血压、维持血栓形成与纤维蛋白溶解之间的平衡、参与免疫系统反应以及新生血管形成。这些功能中任何一项受到干扰都可能导致不同疾病的发生,例如高血压、动脉粥样硬化、深静脉血栓形成以及癌症。