Laboratory of Intestinal Immunology, École Polytechnique Fédérale de Lausanne EPFL, Global Health Institute, Station 19, Lausanne 1015 Switzerland.
Laboratory for Mucosal Immunity, Center for Integrative Medical Sciences (IMS-RCAI), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.
Immunity. 2014 Apr 17;40(4):455-7. doi: 10.1016/j.immuni.2014.04.003.
Eosinophils are found in abundance in the gut. In this issue of Immunity, Chu et al. (2014) report that eosinophil-deficient mice have impaired intestinal immunoglobulin A production, accompanied by a disrupted mucosal layer and alterations in microbiota density and composition.
嗜酸性粒细胞在肠道中大量存在。在本期《免疫》杂志中，Chu 等人（2014 年）报道称，嗜酸性粒细胞缺失的小鼠肠道免疫球蛋白 A 的产生受损，同时伴有黏膜层破坏以及微生物密度和组成改变。
