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尿 pentraxins。

Peeing pentraxins.

机构信息

Department of Molecular Genetics & Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

Department of Molecular Genetics & Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA; Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA; Program in Emerging Infectious Diseases, Duke-National University of Singapore, Singapore 169857, Singapore.

出版信息

Immunity. 2014 Apr 17;40(4):460-2. doi: 10.1016/j.immuni.2014.03.006.

DOI:10.1016/j.immuni.2014.03.006
PMID:24745330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4391336/
Abstract

Antimicrobial agents secreted into urine potentially play a powerful role in the defense of the urinary tract. In this issue of Immunity, Jaillon et al. (2014) describe a role for pentraxin 3 molecules in complementing the host's cellular innate immune responses to uropathogens.

摘要

抗菌剂分泌到尿液中可能在尿路防御中发挥强大作用。在本期《免疫》杂志中,Jaillon 等人(2014)描述了五聚素 3 分子在补充宿主细胞固有免疫对尿路病原体反应方面的作用。

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Peeing pentraxins.尿 pentraxins。
Immunity. 2014 Apr 17;40(4):460-2. doi: 10.1016/j.immuni.2014.03.006.
2
Innate immunity: A wee protection.固有免疫:一种微小的保护。
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Re: The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.回复:体液模式识别分子PTX3是抗尿路感染固有免疫的关键组成部分。
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The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.体液模式识别分子 PTX3 是固有免疫对抗尿路感染的关键组成部分。
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Pattern recognition by pentraxins.五聚体蛋白的模式识别
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The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity.长链五聚体蛋白PTX3作为一种典型的体液模式识别受体:与细胞固有免疫的相互作用。
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The leucocyte migration test in urinary tract infection.尿路感染中的白细胞迁移试验。
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[Serotyping of E. coli in urinary tract infections].[尿路感染中大肠杆菌的血清分型]
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引用本文的文献

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The natural immune molecules urinary Tamm-Horsfall protein and pentraxin 3 as predictors for recurrent urinary tract infection severity: a single-center self-control study.天然免疫分子尿Tamm-Horsfall蛋白和五聚素3作为复发性尿路感染严重程度的预测指标:一项单中心自身对照研究
Ren Fail. 2025 Dec;47(1):2449574. doi: 10.1080/0886022X.2024.2449574. Epub 2025 Jan 8.
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Acute phase proteins patterns as biomarkers in bacterial infection: Recent insights.急性相蛋白模式作为细菌感染的生物标志物:最新见解。
Open Vet J. 2024 Oct;14(10):2539-2550. doi: 10.5455/OVJ.2024.v14.i10.4. Epub 2024 Oct 31.
3
Pentraxin 3: a powerful orchestrator in urinary tract infection.

本文引用的文献

1
The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.体液模式识别分子 PTX3 是固有免疫对抗尿路感染的关键组成部分。
Immunity. 2014 Apr 17;40(4):621-32. doi: 10.1016/j.immuni.2014.02.015.
2
Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation.造血干细胞移植后遗传性纤溶酶原激活物抑制因子-3 缺乏与曲霉菌病
N Engl J Med. 2014 Jan 30;370(5):421-32. doi: 10.1056/NEJMoa1211161.
3
An integrated view of humoral innate immunity: pentraxins as a paradigm.体液先天免疫的综合观点:五聚素作为范例。
五聚体蛋白3:尿路感染中的强大协调者
Nanotheranostics. 2021 May 12;5(4):445-447. doi: 10.7150/ntno.60901. eCollection 2021.
Annu Rev Immunol. 2010;28:157-83. doi: 10.1146/annurev-immunol-030409-101305.
4
Antimicrobial mechanisms of the urinary tract.尿路的抗菌机制。
J Mol Med (Berl). 2008 Jan;86(1):37-47. doi: 10.1007/s00109-007-0256-4. Epub 2007 Sep 6.
5
The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection.抗菌肽cathelicidin可保护尿路免受侵袭性细菌感染。
Nat Med. 2006 Jun;12(6):636-41. doi: 10.1038/nm1407. Epub 2006 Jun 4.
6
Dual function of the long pentraxin PTX3 in resistance against pulmonary infection with Klebsiella pneumoniae in transgenic mice.长五聚体蛋白PTX3在转基因小鼠抗肺炎克雷伯菌肺部感染中的双重作用
Microbes Infect. 2006 Apr;8(5):1321-9. doi: 10.1016/j.micinf.2005.12.017. Epub 2006 Mar 24.
7
Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism.Tamm-Horsfall糖蛋白通过一种Toll样受体4依赖性机制将先天免疫细胞激活与适应性免疫联系起来。
J Clin Invest. 2005 Feb;115(2):468-75. doi: 10.1172/JCI22720.
8
Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli.基质细胞和造血细胞上的Toll样受体4介导对尿路致病性大肠杆菌的天然抗性。
Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4203-8. doi: 10.1073/pnas.0736473100. Epub 2003 Mar 24.
9
Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response.长五聚体蛋白PTX3在抗真菌固有免疫反应中的非冗余作用。
Nature. 2002 Nov 14;420(6912):182-6. doi: 10.1038/nature01195.
10
Urine as a medium for bacterial growth.尿液作为细菌生长的介质。
Lancet. 1966 Nov 12;2(7472):1037-41. doi: 10.1016/s0140-6736(66)92023-x.