Department of Allergology, Medical University of Gdansk, Debinki 7, Gdańsk 80-210, Poland.
Allergy Unit, Azienda Ospedaliera Universitaria Integrata of Verona, Piazzale Aristide Stefani 1, 37126, Verona, Italy.
Immunol Allergy Clin North Am. 2014 May;34(2):365-81. doi: 10.1016/j.iac.2014.02.004. Epub 2014 Mar 15.
Hymenoptera venom allergy is a typical IgE-mediated reaction caused by sensitization to 1 or more allergens of the venom, and accounts for 1.5% to 34% of all cases of anaphylaxis. Patients suffering from mastocytosis are more susceptible to the anaphylactic reactions to an insect sting. This article aims to answer the most important clinical questions raised by the diagnosis and treatment of insect venom allergy in mastocytosis patients. Total avoidance of Hymenoptera is not feasible, and there is no preventive pharmacologic treatment available, although venom immunotherapy reduces the risk of subsequent systemic reactions.
蜂类毒液过敏是一种典型的 IgE 介导的反应，由对毒液中的 1 种或多种过敏原致敏引起，占所有过敏反应的 1.5%至 34%。肥大细胞病患者更易发生昆虫叮咬引起的过敏反应。本文旨在回答肥大细胞病患者昆虫毒液过敏诊断和治疗中提出的最重要的临床问题。完全避免蜂类是不可行的，也没有可用的预防性药物治疗，尽管毒液免疫疗法可降低随后发生全身性反应的风险。
