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渗透性脱髓鞘综合征:一例儿科病例报告及系统文献综述。

Osmotic demyelination syndrome: A pediatric case report and a systematic literature review.

作者信息

Mouhcine Y, Ezzoulali Z, Ouazzani H, Chaouche I, Akammar A, Bouardi N El, Alami B, Lamrani Y Alaoui, Maaroufi M, Boubbou M

机构信息

Department of Mother and Child Radiology-Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, Fez, Morocco.

Department of Radiology-Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, Morocco.

出版信息

Radiol Case Rep. 2025 Jun 19;20(9):4449-4455. doi: 10.1016/j.radcr.2025.05.084. eCollection 2025 Sep.

Abstract

Osmotic Demyelination Syndrome (ODS) is a life-threatening neurologic disorder including two distinct types of demyelination: Central Pontine Myelinolysis (CPM) and Extrapontine Myelinolysis (EPM). While it's clear that the fast correction of low sodium levels is a key precipitating factor, the underlying pathophysiological mechanisms that cause ODS are still being explored. The present paper describes a case of an eleven-year-old male patient diagnosed with ODS based on typical imaging findings. This case report sounds like it could be significant by providing a thorough overview of the pathological findings, clinical outcomes, and imaging findings associated with this condition, particularly in pediatric cases. It also demonstrates the crucial role of MRI in diagnosing this condition.

摘要

渗透性脱髓鞘综合征(ODS)是一种危及生命的神经系统疾病,包括两种不同类型的脱髓鞘:中央脑桥髓鞘溶解症(CPM)和脑桥外髓鞘溶解症(EPM)。虽然低钠水平的快速纠正显然是一个关键的促发因素,但导致ODS的潜在病理生理机制仍在探索中。本文描述了一例11岁男性患者,根据典型的影像学表现诊断为ODS。该病例报告通过全面概述与该疾病相关的病理结果、临床结局和影像学表现,特别是儿科病例,似乎具有重要意义。它还展示了MRI在诊断该疾病中的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e07c/12221483/aee377f202c8/gr1.jpg

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