Kamiya Kazutaka, Shimizu Kimiya, Igarashi Akihito, Kobashi Hidenaga, Sato Nobuyuki, Ishii Rie
From the Department of Ophthalmology, University of Kitasato School of Medicine, Kanagawa, Japan.
From the Department of Ophthalmology, University of Kitasato School of Medicine, Kanagawa, Japan.
J Cataract Refract Surg. 2014 Jun;40(6):963-70. doi: 10.1016/j.jcrs.2013.12.013. Epub 2014 Apr 17.
To compare the biomechanical changes after femtosecond lenticule extraction and small-incision lenticule extraction for myopia.
Department of Ophthalmology, Kitasato University, Kanagawa, Japan.
Comparative case series.
In eyes of consecutive patients, femtosecond lenticule extraction was performed in 1 eye and small-incision lenticule extraction in the other eye (both Visumax laser) by random assignment. Corneal hysteresis (CH) and the corneal resistance factor (CRF) were quantitatively assessed using a dynamic bidirectional applanation device (Ocular Response Analyzer) in relation to the amount of myopic correction preoperatively and 1 week and 1 and 3 months postoperatively.
This study comprised 48 eyes (24 patients). The decrease in CH and the CRF was statistically significant 1 week after both lenticule extraction procedures; however, the changes subsequently stabilized with no further deterioration (P<.001). There were no statistically significant differences between the biomechanical changes in the 2 procedures at any time; however, a significant correlation was found between the changes and the myopic correction 3 months after femtosecond lenticule extraction (r = 0.41, P=.046, CH; r = 0.41, P=.045, CRF) and after small-incision lenticule extraction (r = 0.62, P=.001, CH; r = 0.67, P<.001, CRF).
The greatest changes in biomechanical parameters occurred within 1 week after femtosecond lenticule extraction and small-incision lenticule extraction; the changes were then nearly stable in relation to the amount of myopic correction. This suggests that the presence or absence of flap lifting does not significantly affect biomechanical parameters.
No author has a financial or proprietary interest in any material or method mentioned.
比较飞秒透镜切除术和小切口透镜切除术治疗近视后的生物力学变化。
日本神奈川县北里大学眼科。
比较病例系列。
在连续患者的眼中，通过随机分配，一只眼行飞秒透镜切除术，另一只眼行小切口透镜切除术（均使用Visumax激光）。使用动态双向压平装置（眼反应分析仪），术前、术后1周、1个月和3个月，根据近视矫正量，定量评估角膜滞后（CH）和角膜阻力因子（CRF）。
本研究纳入48只眼（24例患者）。两种透镜切除术后1周，CH和CRF的降低具有统计学意义；然而，随后变化稳定，未进一步恶化（P<0.001）。两种手术在任何时间的生物力学变化之间均无统计学显著差异；然而，飞秒透镜切除术后3个月（r = 0.41，P = 0.046，CH；r = 0.41，P = 0.045，CRF）和小切口透镜切除术后3个月（r = 0.62，P = 0.001，CH；r = 0.67，P<0.001，CRF），发现变化与近视矫正量之间存在显著相关性。
飞秒透镜切除术和小切口透镜切除术后1周内，生物力学参数变化最大；随后，与近视矫正量相关的变化几乎稳定。这表明是否掀起角膜瓣对生物力学参数无显著影响。
没有作者对文中提及的任何材料或方法拥有财务或专利权益。
