人胎盘中存在的脱嘌呤/脱嘧啶内切核酸酶的切割机制。
Mechanism of incision by an apurinic/apyrimidinic endonuclease present in human placenta.
作者信息
Haukanes B I, Wittwer C U, Helland D E
机构信息
Laboratory of Biotechnology, University of Bergen, Tromsø, Norway.
出版信息
Nucleic Acids Res. 1989 Jul 25;17(14):5529-35. doi: 10.1093/nar/17.14.5529.
Abstract
An apparently homogeneous enzyme preparation, containing an apurinic/apyrimidinic (AP) endonuclease from human placenta, was by DNA sequencing analysis found to act as a class I AP-endonuclease, i.e. produce a 3'-deoxyribose and 5'-phosphomonoester nucleotide termini.
摘要
一种明显均一的酶制剂，含有来自人胎盘的脱嘌呤/脱嘧啶（AP）内切核酸酶，经DNA测序分析发现其作为I类AP内切核酸酶起作用，即产生3'-脱氧核糖和5'-磷酸单酯核苷酸末端。
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