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[Oleoma: A case report with good response to tetracycline].[油瘤:一例对四环素治疗反应良好的病例报告]
Dermatol Online J. 2010 Oct 15;16(10):7.
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Foreign body granuloma formation secondary to silicone injection.硅酮注射继发的异物肉芽肿形成
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Breast paraffinoma.乳腺石蜡瘤
Breast J. 2008 Sep-Oct;14(5):504-5. doi: 10.1111/j.1524-4741.2008.00633.x. Epub 2008 Jul 24.
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Adverse granulomatous reaction after cosmetic dermal silicone injection.美容性真皮内注射硅酮后的不良肉芽肿反应。
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注射液态硅胶隆乳后出现类似皮肤黄色瘤的脂肪瘤。

Oleomas mimicking cutaneous xanthomas following breast augmentation by injection of liquid silicone.

作者信息

González-Sabín Marta, Almagro-Sánchez Manuel, Iglesias-Conde Raquel, Felgueiras-Magalhaes Joao Luis

机构信息

Department of Dermatology, Complejo Hospitalario Universitario A Coruña, Spain.

出版信息

J Dermatol Case Rep. 2014 Mar 31;8(1):13-5. doi: 10.3315/jdcr.2014.1163.

DOI:10.3315/jdcr.2014.1163
PMID:24748905
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3989091/
Abstract

BACKGROUND

Oleoma is defined as a foreign body granuloma resulting from the injection of oily substances into the skin or subcutaneous tissue. Liquid injectable silicone has been used extensively over the last five decades for soft tissue augmentation. Although initially considered as a biologically inert material, it has been implicated in a variety of adverse reactions, sometimes with latent periods of decades.

MAIN OBSERVATIONS

We describe the case of a 44-year-old Peruvian woman presenting with multiple painless yellowish papules and plaques limited to the lower half of the breasts, that seemed to be cutaneous xanthomas. A skin biopsy showed granulomatous inflammation with multiple clear vacuoles corresponding to injected liquid silicone particles, diagnosed as oleoma. The patient was then re-evaluated and she reported that she underwent breast augmentation by injection of liquid silicone five prior to presentation in our department. Thus, the diagnosis of oleoma was confirmed.

CONCLUSIONS

We describe a case with yellowish papules on both breasts in a woman that underwent breast augmentation by injection of liquid silicone. Since this unusual presentation of oleomas can be confused with cutaneous xanthomas, a biopsy is essential for diagnosis.

摘要

背景

油瘤被定义为由于向皮肤或皮下组织注射油性物质而导致的异物肉芽肿。在过去的五十年中,可注射液态硅胶被广泛用于软组织填充。尽管最初被认为是一种生物惰性材料,但它已被证明与多种不良反应有关,有时潜伏期长达数十年。

主要观察结果

我们描述了一名44岁秘鲁女性的病例,该患者双侧乳房下半部出现多个无痛性淡黄色丘疹和斑块,看似皮肤黄瘤。皮肤活检显示肉芽肿性炎症,有多个透明空泡,对应于注射的液态硅胶颗粒,诊断为油瘤。随后对患者进行了重新评估,她报告说在来我院就诊前五年曾接受过液态硅胶注射隆胸。因此,油瘤诊断得以确诊。

结论

我们描述了一名通过注射液态硅胶隆胸的女性双侧乳房出现淡黄色丘疹的病例。由于油瘤的这种不寻常表现可能与皮肤黄瘤相混淆,因此活检对于诊断至关重要。