Kim Ahlee, Yang Hye Ran, Moon Jin Soo, Chang Ju Young, Ko Jae Sung
Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.
Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Pediatr Gastroenterol Hepatol Nutr. 2014 Mar;17(1):57-60. doi: 10.5223/pghn.2014.17.1.57. Epub 2014 Mar 31.
Acute acalculous cholecystitis (AAC) is an inflammation of the gallbladder in the absence of demonstrated stones. AAC is frequently associated with severe systemic inflammation. However, the exact etiology and pathogenesis of AAC still remain unclear. Acute infection with Epstein Barr virus (EBV) in childhood is usually aymptomatic, whereas it often presents as typical infectious mononucleosis symptoms such as fever, cervical lymphadenopathy, and hepatosplenomegaly. AAC may occur during the course of acute EBV infection, which is rarely encountered in the pediatric population. AAC complicating the course of a primary EBV infection is usually associated with a favorable outcome. Most of the patients recover without any surgical treatment. Therefore, the detection of EBV in AAC would be important for prediction of better prognosis. We describe the case of a 10-year-old child who presented with AAC during the course of primary EBV infection, the first in Korea, and review the relevant literature.
急性非结石性胆囊炎（AAC）是指在未发现结石的情况下胆囊发生的炎症。AAC常与严重的全身炎症相关。然而，AAC的确切病因和发病机制仍不清楚。儿童时期感染爱泼斯坦-巴尔病毒（EBV）通常无症状，而其往往表现为典型的传染性单核细胞增多症症状，如发热、颈部淋巴结病和肝脾肿大。AAC可能在急性EBV感染过程中发生，这在儿科人群中很少见。原发性EBV感染过程中并发AAC通常预后良好。大多数患者无需任何手术治疗即可康复。因此，在AAC中检测EBV对于预测更好的预后很重要。我们描述了一名10岁儿童在原发性EBV感染过程中出现AAC的病例，这是韩国首例，并对相关文献进行了综述。
