Young Callan, Lampe Richard
Pediatrics, Texas A&M College of Medicine, Dallas, USA.
Pediatrics, Texas Tech University Health Sciences Center, Lubbock, USA.
Cureus. 2019 Jun 30;11(6):e5044. doi: 10.7759/cureus.5044.
Epstein-Barr Virus (EBV) is estimated to infect greater than 98% of adults worldwide and is one of the most common human viruses. EBV infection can lead to acute infectious mononucleosis characterized by fever, fatigue, malaise, sore throat, and lymphadenopathy. Elevated liver function tests (LFTs) and hepatosplenomegaly may also be present. This infection usually lasts over a period of weeks or months and is self-limited. Infected individuals, however, may suffer rare complications. Acute acalculous cholecystitis (AAC) is an atypical complication of infectious mononucleosis. The case of a young healthy adolescent female with primary EBV infection complicated by AAC is reported. Providers should be aware that many pediatric and adult cases of AAC due to EBV resolve with conservative treatment. Surgical intervention has not been described as necessary or indicated in the context of AAC caused by EBV and should only be considered in severe cases that are not responding to conservative therapy.
据估计，爱泼斯坦-巴尔病毒（EBV）在全球感染了超过98%的成年人，是最常见的人类病毒之一。EBV感染可导致以发热、疲劳、不适、喉咙痛和淋巴结病为特征的急性传染性单核细胞增多症。肝功能检查（LFTs）升高和肝脾肿大也可能出现。这种感染通常持续数周或数月，具有自限性。然而，受感染个体可能会出现罕见的并发症。急性非结石性胆囊炎（AAC）是传染性单核细胞增多症的一种非典型并发症。本文报告了一例原发性EBV感染并发AAC的年轻健康青少年女性病例。医疗服务提供者应意识到，许多因EBV引起的儿科和成人AAC病例通过保守治疗即可痊愈。在由EBV引起的AAC病例中，尚未有手术干预被描述为必要或适用的情况，仅在对保守治疗无反应的严重病例中才应考虑手术干预。
