Cho Woo Kyung, Kang Sung Min, Lee Jungkyu K
J Nanosci Nanotechnol. 2014 Feb;14(2):1231-52. doi: 10.1166/jnn.2014.8891.
Nanoarchitectured polymer thin films are playing an increasingly pivotal role in a wide range of areas such as interfacial reactions, biomedical devices/implants, biosensors, food packing, and marine equipment. This review highlights recent research results in the field of the non-biofouling polymer films, including current understanding of the mechanisms of non-biofouling efficacy against bioentities (for example, proteins, cells, and bacteria) under different biological conditions. We also discuss current advances in the fabrication of non-biofouling coatings and micropatterns of cells on solid substrates and suggest a guideline when designing a non-biofouling polymer films, according to application requirements.
纳米结构聚合物薄膜在界面反应、生物医学设备/植入物、生物传感器、食品包装和海洋设备等广泛领域中发挥着越来越关键的作用。本综述重点介绍了非生物污损聚合物薄膜领域的最新研究成果，包括当前对不同生物条件下对生物实体（如蛋白质、细胞和细菌）的非生物污损功效机制的理解。我们还讨论了在固体基质上制备非生物污损涂层和细胞微图案的当前进展，并根据应用要求为设计非生物污损聚合物薄膜提供了指导方针。
