爪哇豆蔻果实中的单萜类化合物。
Monoterpenes from the fruits of Amomum kravanh.
作者信息
Luo Jian-Guang, Yin Hong, Kong Ling-Yi
机构信息
a State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing 210009 , China.
出版信息
J Asian Nat Prod Res. 2014;16(5):471-5. doi: 10.1080/10286020.2014.906405. Epub 2014 Apr 22.
Two new monoterpenes, (7S)-p-cymene-2,7,8-triol (1) and (3R,4R,6S)-p-menth-1-ene-3,6,10-triol (2), were isolated from the fruits of Amomum kravanh. Their structures were established by spectroscopic data. The absolute configuration of the 7,8-diol moiety in 1 was assigned by CD data after addition of Mo2(OAc)4 in dimethyl sulfoxide (DMSO) solution. Compounds 1 and 2 exhibited weak activity of anti-platelet aggregation in vitro.
从白豆蔻果实中分离得到两个新的单萜类化合物，(7S)-对伞花烃-2,7,8-三醇（1）和(3R,4R,6S)-对薄荷-1-烯-3,6,10-三醇（2）。通过光谱数据确定了它们的结构。在二甲基亚砜（DMSO）溶液中加入四乙酸钼（IV）后，通过圆二色（CD）数据确定了化合物1中7,8-二醇部分的绝对构型。化合物1和2在体外表现出较弱的抗血小板聚集活性。
Zotero 插件