原位恶性黑色素瘤对基底细胞癌的一种侵袭，类似恶性基底黑素细胞瘤。

A colonization of basal cell carcinoma by malignant melanoma in situ resembling a malignant basomelanocytic tumor.

作者信息

Goeser Megan, DiMaio Dominick J

机构信息

*University of Nebraska Medical School, Omaha, NE; and †Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE.

出版信息

Am J Dermatopathol. 2014 Nov;36(11):e179-82. doi: 10.1097/DAD.0000000000000047.

DOI:10.1097/DAD.0000000000000047

PMID:24752214

Abstract

We report a case of colonization of basal cell carcinoma (BCC) by malignant melanoma in situ (MIS) simulating a malignant basomelanocytic tumor. A biopsy of a pigmented lesion present on an 83-year-old man's scalp displayed intimate admixing of basaloid and melanocytic cells. This seemingly inseparable combination of BCC and neoplastic melanocytes has been referred to as a malignant basomelanocytic tumor. However, our case also displays an adjacent component of MIS, thus favoring colonization of BCC by MIS as the etiology. To our knowledge, this is the third case report of colonization of BCC by MIS resembling a malignant basomelanocytic tumor.

摘要

我们报告了一例原位恶性黑色素瘤（MIS）定植于基底细胞癌（BCC）的病例，该病例模拟了恶性基底黑素细胞瘤。一名83岁男性头皮上出现的色素沉着病变活检显示基底样细胞和黑素细胞紧密混合。基底细胞癌和肿瘤性黑素细胞这种看似不可分割的组合被称为恶性基底黑素细胞瘤。然而，我们的病例还显示了一个相邻的原位恶性黑色素瘤成分，因此支持原位恶性黑色素瘤定植于基底细胞癌作为病因。据我们所知，这是第三例原位恶性黑色素瘤定植于基底细胞癌并类似恶性基底黑素细胞瘤的病例报告。