Chen Li-Hua, Yue Guo-Chao, Guan Yong-Mei, Yang Ming, Zhu Wei-Feng
Zhongguo Zhong Yao Za Zhi. 2014 Jan;39(1):65-70.
To investigate such physical indexes as hygroscopicity, angle of repose, bulk density, fillibility of compression of mixed powder of directly compressed auxiliary materials and fermented cordyceps powder by using micromeritic study methods. The results showed that spray-dried lactose Flowlac100 and microcrystalline cellulose Avicel PH102 had better effect in liquidity and compressibility on fermented cordyceps powder than pregelatinized starch. The study on the impact of directly compressed auxiliary materials on the powder property of fermented cordyceps powder had guiding significant to the research of fermented cordyceps powder tablets, and could provide basis for the development of fermented cordyceps powder tablets.
采用粉体学研究方法,考察直接压片辅料与发酵虫草菌粉混合粉末的吸湿性、休止角、堆密度、压缩成型性等物理指标。结果表明,喷雾干燥乳糖Flowlac100和微晶纤维素Avicel PH102对发酵虫草菌粉的流动性和可压性的改善作用优于预胶化淀粉。研究直接压片辅料对发酵虫草菌粉粉体性质的影响,对发酵虫草菌粉片剂的研究具有重要指导意义,可为发酵虫草菌粉片剂的开发提供依据。