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补肾活血促排卵复方治疗多囊卵巢综合征致排卵障碍性不孕症的临床疗效观察

[Clinical efficacy observation on therapy ovulation failure infertility caursed by PCOS with reinforcing kidney, activating blood circulation and ovarian stimulation compound recipe].

作者信息

Jin Xuan-Ting, Ma Kun, Shan Jing

出版信息

Zhongguo Zhong Yao Za Zhi. 2014 Jan;39(1):140-3.

PMID:24754183
Abstract

To investigate the clinical effect of tonifying the kidney and promoting blood circulation to promote oocyte decoction in the treatment of anovulatory infertility caused by polycystic ovary syndrome. Sixty cases were selected from the out-patient department of Xiyuan hospital of China academy of Chinese medical sciences and the Chinese academy of traditional Chinese medicine, Chinese medicine out-patient department. Sixty patients with PCOS patients were randomly divided into the treatment group and the control group, with 30 cases and 30 cases respectively. The treatment group was given decoction of the reinforcing kidney, activating blood circulation and ovarian stimulation compound recipe. The control group was treated with clomiphene. Through the treatment of 1-2 courses, in the treatment group the pregnancy rate was 56.67%, the ovulation rate 61%; in control group of clomiphene citrate ovulation ratepregnancy rate was 30% , 72.84% of ovulation rate. The difference was significant between two groups (P < 0.05), the pregnancy rate in the treatment group was higher than the control group. The treatment group has regulatory effect on FSH, LH and their ratio, and increase E2 level, decrease T, PRL, INS and other hormone levels, contributing to the mature development of the follicles and endometrium growth, increase the ovulation rate and pregnancy rate. The control group on FSH, E2 increased, LH, T, PRL and INS showed no obvious effect.

摘要

探讨补肾活血促排卵汤治疗多囊卵巢综合征所致无排卵性不孕症的临床疗效。选取中国中医科学院西苑医院及中国中医科学院门诊部的门诊患者60例。将60例多囊卵巢综合征患者随机分为治疗组和对照组,各30例。治疗组给予补肾活血促排卵复方汤剂,对照组给予克罗米芬。经过1 - 2个疗程的治疗,治疗组妊娠率为56.67%,排卵率为61%;对照组克罗米芬的排卵率为72.84%,妊娠率为30%。两组差异有统计学意义(P < 0.05),治疗组妊娠率高于对照组。治疗组对促卵泡生成素(FSH)、促黄体生成素(LH)及其比值有调节作用,可提高雌二醇(E2)水平,降低睾酮(T)、泌乳素(PRL)、胰岛素(INS)等激素水平,有助于卵泡成熟发育及子宫内膜生长,提高排卵率和妊娠率。对照组对FSH、E2升高,LH、T、PRL和INS无明显影响。

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[Clinical efficacy observation on therapy ovulation failure infertility caursed by PCOS with reinforcing kidney, activating blood circulation and ovarian stimulation compound recipe].补肾活血促排卵复方治疗多囊卵巢综合征致排卵障碍性不孕症的临床疗效观察
Zhongguo Zhong Yao Za Zhi. 2014 Jan;39(1):140-3.
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Effects of human chorionic gonadotropin combined with clomiphene on Serum E, FSH, LH and PRL levels in patients with polycystic ovarian syndrome.
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