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手术联合复方倍他米松皮损内注射治疗耳廓瘢痕疙瘩

[Treatment of auricular keloids with surgery and intralesional injection of compound betamethasone].

作者信息

Wang Fang, Yang Honghua, Liao Huaiwei, Li Wenfang, Liu Wei

出版信息

Zhonghua Zheng Xing Wai Ke Za Zhi. 2014 Jan;30(1):7-10.

Abstract

OBJECTIVE

To investigate the treatment of auricular keloid with dinuclear surgery and intralesional injection of compound Betamethasone.

METHODS

From Jan. 2008 to Jan. 2012, a total of 186 cases of ear keloid were treated by surgery only (22 cases), or intralesional injection of compound Betamethasone (34 cases), or combined dinuclear surgery with compound Betamethasone (130 cases). All the patients were followed up for one year. SPSS 16.0 software was used for statistical processing and analysis, and GraphPad inspection method for inspection.

RESULTS

The effective rate was 54.55% (12/ 22) in surgery group and 55.88% (19/34)in injection group. The recurrence was obvious in injection group during the follow-up period. The effective rate was as high as 96.92% (126/130) in combined group with recurrence in 4 cases, which was significantly higher than that in other 2 groups (P < 0. 01).

CONCLUSION

Combined dinuclear surgery and compound Betamethasone injection has a good therapeutic effect on auricular keloids.

摘要

目的

探讨双核手术联合复方倍他米松皮损内注射治疗耳部瘢痕疙瘩的疗效。

方法

选取2008年1月至2012年1月期间收治的耳部瘢痕疙瘩患者186例,其中单纯手术治疗22例,复方倍他米松皮损内注射治疗34例,双核手术联合复方倍他米松治疗130例。所有患者均随访1年。采用SPSS 16.0软件进行统计学处理与分析,采用GraphPad检验方法进行检验。

结果

手术组有效率为54.55%(12/22),注射组有效率为55.88%(19/34)。随访期间注射组复发明显。联合组有效率高达96.92%(126/130),复发4例,明显高于其他两组(P<0.01)。

结论

双核手术联合复方倍他米松注射治疗耳部瘢痕疙瘩疗效良好。

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