a Norwegian Institute for Water Research (NIVA) , Oslo , Norway.
J Toxicol Environ Health A. 2014;77(9-11):550-6. doi: 10.1080/15287394.2014.887419.
Herring gull eggs from two locations in Norway, an island situated in the north (Musvær, 69.88° N, 18.55° E) and an island in the southeast (Reiaren, 59.15° N, 10.46° E) of the country, were analyzed for the presence of aryl hydrocarbon receptor (AhR) agonists. AhR agonist activity was determined using the dioxin-responsive chemically activated luciferase expression (DR-CALUX) assay to calculate the toxic equivalent quotient (TEQ)CALUX. TEQCALUX ranged from 16 to 401 pg TEQ/g lipid in the samples from the north (n = 11) and between 6 and 360 pg TEQ/g lipid (n = 12) in the southeastern samples. The large variance between the individual samples is postulated to be due to different feeding habits of individual birds. The levels of AhR agonists detected might lead to adverse effects for the developing embryo or to a significant increase of contaminant load for human consumers of eggs.
对来自挪威两个地点（一个位于该国北部的岛屿 Musvær，北纬 69.88°，东经 18.55°；另一个位于东南部的岛屿 Reiaren，北纬 59.15°，东经 10.46°）的鲱鸥卵进行了分析，以检测是否存在芳基烃受体（AhR）激动剂。使用二恶英反应性化学激活荧光素酶表达（DR-CALUX）测定法测定 AhR 激动剂活性，以计算毒效当量商（TEQCALUX）。来自北部的样本（n = 11）的 TEQCALUX 范围为 16 至 401 pg TEQ/g 脂质，来自东南部的样本（n = 12）的 TEQCALUX 范围为 6 至 360 pg TEQ/g 脂质。推测个体样本之间的差异较大是由于个体鸟类的不同觅食习惯所致。检测到的 AhR 激动剂水平可能会对发育中的胚胎产生不利影响，或者会使食用鸡蛋的人类消费者的污染物负荷显著增加。
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