Simple D. Singh, A. Blythe Ryerson, and Manxia Wu are with the Cancer Surveillance Branch, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA. Judith S. Kaur is with the Department of Oncology, Mayo Clinic, Rochester, MN.
Am J Public Health. 2014 Jun;104 Suppl 3(Suppl 3):S423-31. doi: 10.2105/AJPH.2013.301781. Epub 2014 Apr 22.
We examined geographic differences and trends in incidence and mortality of ovarian and uterine cancer in American Indian/Alaska Native (AI/AN) women.
We linked mortality data (1990-2009) and incidence data (1999-2009) to Indian Health Service (IHS) records. Death (and incidence) rates for ovarian and uterine cancer were examined for AI/AN and White women; Hispanics were excluded. Analyses focused on Contract Health Service Delivery Area (CHSDA) counties.
AI/AN and White women had similar ovarian and uterine cancer death rates. Ovarian and uterine cancer incidence and death rates were higher for AI/ANs residing in CHSDA counties than for all US counties. We also observed geographic differences, regardless of CHSDA residence, in ovarian and uterine cancer incidence and death rates in AI/AN women by IHS region; Pacific Coast and Southern Plains women had higher ovarian cancer death rates and Northern Plains women had higher uterine cancer death rates.
Regional differences in the incidence and mortality of ovarian and uterine cancers among AI/AN women in the United States were significant. More research among correctly classified AI/AN women is needed to understand these differences.
我们研究了美国印第安人/阿拉斯加原住民（AI/AN）女性卵巢癌和子宫癌的发病率和死亡率的地域差异和趋势。
我们将死亡率数据（1990-2009 年）和发病率数据（1999-2009 年）与印第安卫生服务（IHS）记录相关联。研究了 AI/AN 和白人女性的卵巢癌和子宫癌死亡率；排除了西班牙裔。分析重点是合同医疗服务提供区（CHSDA）县。
AI/AN 和白人女性的卵巢癌和子宫癌死亡率相似。居住在 CHSDA 县的 AI/AN 女性的卵巢癌和子宫癌发病率和死亡率高于所有美国县。我们还观察到，无论 CHSDA 的居住情况如何，AI/AN 女性的卵巢癌和子宫癌发病率和死亡率在 IHS 地区都存在地域差异；太平洋沿岸和南部平原的女性卵巢癌死亡率较高，北部平原的女性子宫癌死亡率较高。
美国 AI/AN 女性卵巢癌和子宫癌的发病率和死亡率存在显著的地域差异。需要对正确分类的 AI/AN 女性进行更多的研究，以了解这些差异。
