Vissers D, Neels H, Vermandel A, De Wachter S, Tjalma W A A, Wyndaele J-J, Taeymans J
Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Obes Rev. 2014 Jul;15(7):610-7. doi: 10.1111/obr.12170. Epub 2014 Apr 22.
Although the aetiology of urinary incontinence can be multifactorial, in some cases weight loss could be considered as a part of the therapeutic approach for urinary incontinence in people who are overweight. The objective of this study was to review and meta-analyse the effect of non-surgical weight loss interventions on urinary incontinence in overweight women. Web of Science, PubMed, Pedro, SPORTDiscus and Cochrane were systematically searched for clinical trials that met the a priori set criteria. Data of women who participated in non-surgical weight loss interventions (diet, exercise, medication or a combination) were included in the meta-analysis. After removing duplicates, 62 articles remained for screening on title, abstract and full text. Six articles (totalling 2,352 subjects in the intervention groups) were included for meta-analysis. The mean change in urinary incontinence (reported as frequency or quantity, depending on the study) after a non-surgical weight loss intervention, expressed as standardized effect size and corrected for small sample sizes (Hedges' g), was -0.30 (95%CI = -0.47 to -0.12). This systematic review and meta-analysis shows evidence that a non-surgical weight loss intervention has the potential to improve urinary incontinence and should be considered part of standard practice in the management of urinary incontinence in overweight women.
尽管尿失禁的病因可能是多因素的,但在某些情况下,体重减轻可被视为超重人群尿失禁治疗方法的一部分。本研究的目的是回顾和荟萃分析非手术减肥干预对超重女性尿失禁的影响。对Web of Science、PubMed、Pedro、SPORTDiscus和Cochrane进行系统检索,以查找符合预先设定标准的临床试验。参与非手术减肥干预(饮食、运动、药物或联合干预)的女性数据被纳入荟萃分析。去除重复项后,剩余62篇文章进行标题、摘要和全文筛选。6篇文章(干预组共2352名受试者)被纳入荟萃分析。非手术减肥干预后尿失禁的平均变化(根据研究报告为频率或量),以标准化效应量表示并针对小样本量进行校正(Hedges' g),为-0.30(95%CI = -0.47至-0.12)。这项系统评价和荟萃分析表明,有证据显示非手术减肥干预有可能改善尿失禁,应被视为超重女性尿失禁管理标准实践的一部分。