Gallagher Carla A, Willems Mark E T, Lewis Mark P, Myers Stephen D
Department of Sport and Exercise Sciences, University of Chichester, College Lane, Chichester, West Sussex, PO19 6PE, UK.
Eur J Appl Physiol. 2014 Aug;114(8):1555-62. doi: 10.1007/s00421-014-2882-1. Epub 2014 Apr 23.
This study investigated the response of the ventilatory threshold (VT) to acute normobaric hypoxia and compared the agreement between software-based algorithms which use automatic detection to identify the VT. Results were used to examine whether the VT can be used as a physiological parameter to prescribe and monitor exercise intensity in hypoxic exercise training programs.
Fourteen untrained individuals (7 women, 7 men; age 22 ± 2 years, [Formula: see text]O2peak 46 ± 7 mL kg(-1) min(-1)) completed five identical graded exercise tests (randomized order) on a cycle ergometer to measure VT at sea-level (SL) and in response to four normobaric hypoxic conditions (FIO2: 0.185, 0.165, 0.142, 0.125) equivalent to 1,000, 2,000, 3,000 and 4,000 m. Data were analyzed using a one-way analysis of variance (ANOVA) with repeated measures.
The VT was similar across all conditions (SL = 1.98 ± 0.46, 1,000 m = 2.03 ± 0.61, 2,000 m = 2.27 ± 0.62, 3,000 m = 1.84 ± 0.50, 4,000 m = 2.29 ± 0.58 L min(-1)) for all algorithms used despite a reduction in arterial oxygen saturation at 3,000 (P ≤ 0.01) and 4,000 m (P ≤ 0.01) compared with SL values.
The VT appears to be a suitable physiological parameter for exercise prescription in normobaric hypoxia up to an altitude of 4,000 m.
本研究调查了通气阈（VT）对急性常压性缺氧的反应，并比较了使用自动检测来识别VT的基于软件的算法之间的一致性。研究结果用于检验VT是否可作为生理参数，用于规定和监测低氧运动训练计划中的运动强度。
14名未经训练的个体（7名女性，7名男性；年龄22±2岁，[公式：见原文]O2峰值46±7 mL·kg⁻¹·min⁻¹）在功率自行车上完成了五次相同的分级运动测试（随机顺序），以测量海平面（SL）时的VT以及对四种常压性低氧条件（FIO2：0.185、0.165、0.142、0.125）的反应，这些条件分别相当于海拔1000米、2000米、3000米和4000米。使用重复测量的单因素方差分析（ANOVA）对数据进行分析。
尽管与SL值相比，在海拔3000米（P≤0.01）和4000米（P≤0.01）时动脉血氧饱和度降低，但所有使用的算法在所有条件下（SL = 1.98±0.46，1000米 = 2.03±0.61，2000米 = 2.27±0.62，3000米 = 1.84±0.50，4000米 = 2.29±0.58 L·min⁻¹）下的VT相似。
在高达4000米的常压性低氧环境中，VT似乎是运动处方的合适生理参数。
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