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非伤寒沙门氏菌:失代偿性肝硬化自发性细菌性腹膜炎的一个不常见病因。

Non-typhoidal salmonella: an unusual cause of spontaneous bacterial peritonitis in decompensated cirrhosis.

机构信息

Department of Medical Gastroenterology, Government Medical College, Thiruvananthapuram, Kerala, India

Department of Medical Gastroenterology, Government Medical College, Thiruvananthapuram, Kerala, India.

出版信息

Gastroenterol Rep (Oxf). 2014 Aug;2(3):242-4. doi: 10.1093/gastro/gou018. Epub 2014 Mar 19.

DOI:10.1093/gastro/gou018
PMID:24759352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4124267/
Abstract

Salmonella typhimurium, a non-typhoidal salmonella, is an unusual cause of spontaneous bacterial peritonitis (SBP). It is usually reported in asymptomatic patients with normal or high ascitic fluid protein levels with underlying immunosuppression, as high opsonic activity in the ascitic fluid of these patients protects them from the usual organisms causing spontaneous bacterial peritonitis, unless they are exposed to a particularly virulent organism like salmonella. We report a case of culture-proven non-typhoidal salmonella in a patient with decompensated cirrhosis, with low protein and without any underlying immunosuppression, and no other source to explain its origin.

摘要

鼠伤寒沙门氏菌是一种非伤寒沙门氏菌,是自发性细菌性腹膜炎(SBP)的不常见病因。它通常在无症状患者中报告,这些患者的腹水蛋白水平正常或升高,且存在潜在免疫抑制,因为这些患者的腹水中具有较高的调理活性,可以保护他们免受通常引起自发性细菌性腹膜炎的病原体侵害,除非他们接触到像沙门氏菌这样特别具有毒性的病原体。我们报告了一例在失代偿性肝硬化患者中经培养证实的非伤寒沙门氏菌感染病例,该患者腹水蛋白水平低,且不存在任何潜在免疫抑制,也没有其他来源可以解释其感染源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7070/4124267/2840937d0533/gou018f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7070/4124267/2840937d0533/gou018f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7070/4124267/2840937d0533/gou018f1.jpg

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本文引用的文献

1
Spontaneous bacterial peritonitis from Salmonella: an unusual bacterium with unusual presentation.自发性细菌性腹膜炎由沙门氏菌引起:一种不寻常的细菌引起的不寻常表现。
Hepatol Int. 2008 Sep;2(3):388-9. doi: 10.1007/s12072-008-9087-9. Epub 2008 Jul 25.
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Spontaneous Bacterial Peritonitis Secondary to Salmonella spp. in a Patient With Decompensated Liver Cirrhosis.一名失代偿期肝硬化患者继发于沙门氏菌属的自发性细菌性腹膜炎
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Spontaneous non-typhoidal Salmonella peritonitis in patients with serious underlying disorders.患有严重基础疾病患者的自发性非伤寒沙门氏菌腹膜炎
Infection. 1999 May-Jun;27(3):224-7. doi: 10.1007/BF02561536.
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Evaluation of Salmonella typhimurium mutants in a model of experimental gastroenteritis.鼠伤寒沙门氏菌突变体在实验性肠胃炎模型中的评估
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Risk factors for spontaneous bacterial peritonitis in cirrhotic patients with ascites.肝硬化腹水患者自发性细菌性腹膜炎的危险因素。
Gastroenterology. 1993 Apr;104(4):1133-8. doi: 10.1016/0016-5085(93)90284-j.
8
Opsonic activity of human ascitic fluid: a potentially important protective mechanism against spontaneous bacterial peritonitis.人腹水的调理活性:一种针对自发性细菌性腹膜炎的潜在重要保护机制。
Hepatology. 1985 Jul-Aug;5(4):634-7. doi: 10.1002/hep.1840050419.
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