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Downregulation of miR-214 is specific of liver metastasis in colorectal cancer and could play a role determining the metastatic niche.

作者信息

Cristóbal Ion, Caramés Cristina, Madoz-Gúrpide Juan, Rojo Federico, Aguilera Oscar, García-Foncillas Jesús

机构信息

Translational Oncology Division, Oncohealth Institute, Health Research Institute FJD-UAM, University Hospital, Avda. Reyes Católicos-2, 28040, Madrid, Spain.

出版信息

Int J Colorectal Dis. 2014 Jul;29(7):885. doi: 10.1007/s00384-014-1872-4. Epub 2014 Apr 24.

DOI:10.1007/s00384-014-1872-4
PMID:24760176
Abstract
摘要

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The Role of microRNAs in Development of Colitis-Associated Colorectal Cancer.microRNAs 在结肠炎相关结直肠癌发生发展中的作用。
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MicroRNA-214 targets PTK6 to inhibit tumorigenic potential and increase drug sensitivity of prostate cancer cells.MicroRNA-214 通过靶向作用于 PTK6 抑制前列腺癌细胞的致瘤潜能并增加药物敏感性。
Sci Rep. 2019 Jul 5;9(1):9776. doi: 10.1038/s41598-019-46170-3.
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Epigenetic Regulation by lncRNAs: An Overview Focused on UCA1 in Colorectal Cancer.lncRNAs介导的表观遗传调控：聚焦于结直肠癌中UCA1的概述
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