Houghton Pamela E
School of Physical Therapy, Western University , London, Canada .
Adv Wound Care (New Rochelle). 2014 Feb 1;3(2):166-183. doi: 10.1089/wound.2013.0446.
This invited critical review will summarize an expansive body of literature regarding electrical stimulation (ES) and wound healing. Several clinical reports have been published in which ES has been evaluated as a therapy to speed the closure of chronic wounds. Different forms of ES have been applied in varying ways and described using inconsistent terminology by researchers and clinicians around the world. It is important to compile this research and to critically appraise the findings so that clinicians who are not familiar with this field can interpret the research. More recently, ES has been delivered at subsensory levels (termed microcurrent in this review) using very small electrical devices contained within wound dressing. While these newer technologies have obvious technical advances, what research has been published to date about these new devices has not produced findings that suggest this form of ES can accelerate wound closure. Reviewing a collection of published reports on this subject reveals that not all forms of ES produce beneficial results. Rather, only certain ES protocols such as monophasic pulsed current applied to the wound and biphasic pulsed current current that is applied for 2 h daily to periulcer skin at intensities which produce motor responses have consistently demonstrated positive results. Optimal stimulus parameters and treatment schedule for ES used to treat chronic wounds need to be determined. Researchers publishing in this field should provide detailed information about their ES treatment protocol and use a similar terminology to describe the ES waveform and stimulus parameters.
这篇特邀综述将总结大量关于电刺激(ES)与伤口愈合的文献。已有多篇临床报告发表,其中对ES作为一种加速慢性伤口愈合的疗法进行了评估。世界各地的研究人员和临床医生以不同方式应用了不同形式的ES,并使用了不一致的术语来描述。整理这项研究并严格评估研究结果很重要,这样不熟悉该领域的临床医生就能解读这些研究。最近,通过伤口敷料中包含的非常小的电子设备,在亚感知水平(本综述中称为微电流)进行ES。虽然这些较新的技术有明显的技术进步,但迄今为止发表的关于这些新设备的研究并未得出表明这种形式的ES能加速伤口愈合的结果。回顾关于该主题的一系列已发表报告发现,并非所有形式的ES都能产生有益结果。相反,只有某些ES方案,如应用于伤口的单相脉冲电流以及每天以产生运动反应的强度施加2小时于溃疡周围皮肤的双相脉冲电流,一直显示出积极的结果。用于治疗慢性伤口的ES的最佳刺激参数和治疗方案需要确定。在该领域发表研究的人员应提供有关其ES治疗方案的详细信息,并使用类似的术语来描述ES波形和刺激参数。