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肌肉浸润性膀胱癌和激素抵抗性前列腺癌患者的生活质量

Quality of life in patients with muscle-infiltrating bladder cancer and hormone-resistant prostatic cancer.

作者信息

Fosså S D, Aaronson N, Calais da Silva F, Denis L, Newling D, Hosbach G, Kaalhus O

机构信息

Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo.

出版信息

Eur Urol. 1989;16(5):335-9. doi: 10.1159/000471611.

DOI:10.1159/000471611
PMID:2476317
Abstract

A questionnaire, filled in by the patient, was used to assess the quality of life of 65 patients with previously untreated T2-T4 NX MO bladder cancer and of 67 patients with hormone-resistant prostatic cancer. This study examines the initial questionnaire filled in before any nonsurgical treatment had been started in the patients referred to an oncological ward. The aim was to identify domains in which distress was frequent, in the hope of indicating where treatment directed forward improving the patients' quality of life should be directed. The questionnaires yielded reliable and valid data. Among bladder cancer patients micturition disturbances and sexual problems dominated. Bone pain, fatigue, sexual disturbances and interruption of social relationships were the most frequent and most severe complaints of prostatic cancer patients. It was concluded that routine quality of life evaluation by self-assessment questionnaires is possible in a clinical ward provided some assistance by the nursing staff is available. Future treatment in patients for whom palliation is the main goal of therapy should be concentrated on improving the quality of life in areas where distress is evident. The effect of treatment on quality of life could be monitored by similar questionnaires.

摘要

通过患者填写的问卷,对65例未经治疗的T2-T4 NX MO期膀胱癌患者和67例激素抵抗性前列腺癌患者的生活质量进行了评估。本研究调查了在肿瘤病房接受治疗的患者在开始任何非手术治疗之前填写的初始问卷。目的是确定经常出现困扰的领域,以期指明改善患者生活质量的治疗应针对的方向。问卷产生了可靠且有效的数据。膀胱癌患者中排尿障碍和性问题最为突出。骨痛、疲劳、性障碍和社会关系中断是前列腺癌患者最常见和最严重的主诉。得出的结论是,在临床病房,通过自我评估问卷进行常规生活质量评估是可行的,但护理人员需提供一定帮助。对于以姑息治疗为主要治疗目标的患者,未来的治疗应集中于改善明显存在困扰的领域的生活质量。治疗对生活质量的影响可以通过类似的问卷进行监测。

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Periodic health examination, 1991 update: 3. Secondary prevention of prostate cancer. Canadian Task Force on the Periodic Health Examination.定期健康检查,1991年更新版:3. 前列腺癌的二级预防。加拿大定期健康检查特别工作组。
CMAJ. 1991 Sep 1;145(5):413-28.