子痫前期中的出生体重与甲状腺素结合球蛋白
Birth weight and thyroxine-binding globulin in pre-eclampsia.
作者信息
Lao T T, Chin R K, Panesar N S, Lam Y M
机构信息
Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Shatin, Hong Kong.
出版信息
Gynecol Obstet Invest. 1989;28(1):8-10. doi: 10.1159/000293486.
Plasma concentrations of thyroxine (T4) and thyroxine-binding globulin (TBG) as well as triiodothyronine uptake (T3U) were measured in 32 proteinuric pre-eclamptic patients and 24 normotensive pregnant women at similar gestations in the third trimester. The pre-eclamptic patients had slightly lower TBG, and significantly lower T4, concentrations, which were significantly correlated. They also had significantly lower infant birth weight which was correlated to the TBG and T3U values. There was no correlation between T4 and TBG or between birth weight and TBG or T3U in the normotensive women. It is likely that the correlation between TBG and birth weight in the pre-eclamptic patients reflects the severity of proteinuria in pre-eclampsia.
在孕晚期相似孕周的32例蛋白尿型子痫前期患者和24例血压正常的孕妇中，测量了甲状腺素（T4）、甲状腺素结合球蛋白（TBG）的血浆浓度以及三碘甲状腺原氨酸摄取率（T3U）。子痫前期患者的TBG略低，T4浓度显著降低，且两者显著相关。她们的婴儿出生体重也显著较低，且与TBG和T3U值相关。血压正常的女性中，T4与TBG之间、出生体重与TBG或T3U之间均无相关性。子痫前期患者中TBG与出生体重之间的相关性可能反映了子痫前期蛋白尿的严重程度。
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