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Expression of monocyte chemotactic protein-1/CCL2 in gastric cancer and its relationship with tumor hypoxia.单核细胞趋化蛋白-1/CCL2在胃癌中的表达及其与肿瘤缺氧的关系。
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Expression and clinical significance of CD73 and hypoxia-inducible factor-1α in gastric carcinoma.CD73 和缺氧诱导因子-1α 在胃癌中的表达及临床意义。
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Prognostic value of hypoxia-inducible factor-1 alpha and prolyl 4-hydroxylase beta polypeptide overexpression in gastric cancer.缺氧诱导因子-1α和脯氨酰 4-羟化酶β多肽过表达在胃癌中的预后价值。
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[Expression of hypoxia-inducible factor 1α in gastric cancer and its clinical signficance].[缺氧诱导因子1α在胃癌中的表达及其临床意义]
Zhonghua Yi Xue Za Zhi. 2016 May 17;96(18):1418-23. doi: 10.3760/cma.j.issn.0376-2491.2016.18.007.
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Expression of RAP1B is associated with poor prognosis and promotes an aggressive phenotype in gastric cancer.RAP1B的表达与胃癌预后不良相关，并促进其侵袭性表型。
Oncol Rep. 2015 Nov;34(5):2385-94. doi: 10.3892/or.2015.4234. Epub 2015 Sep 1.
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HIF-1 alpha overexpression correlates with poor overall survival and disease-free survival in gastric cancer patients post-gastrectomy.缺氧诱导因子-1α（HIF-1α）过表达与胃癌患者胃切除术后的总生存期和无病生存期较差相关。
PLoS One. 2014 Mar 10;9(3):e90678. doi: 10.1371/journal.pone.0090678. eCollection 2014.
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CCL2 expression correlates with Snail expression and affects the prognosis of patients with gastric cancer.CCL2的表达与Snail的表达相关，并影响胃癌患者的预后。
Pathol Res Pract. 2017 Mar;213(3):217-221. doi: 10.1016/j.prp.2016.12.013. Epub 2016 Dec 23.
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The expression of HIF-1α in primary hepatocellular carcinoma and its correlation with radiotherapy response and clinical outcome.HIF-1α 在原发性肝细胞癌中的表达及其与放疗反应和临床结局的相关性。
Mol Biol Rep. 2012 Feb;39(2):2021-9. doi: 10.1007/s11033-011-0949-1. Epub 2011 Jun 7.
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Increased expression of C-C motif ligand 2 associates with poor prognosis in patients with gastric cancer after gastrectomy.C-C基序配体2表达增加与胃癌患者胃切除术后预后不良相关。
Tumour Biol. 2016 Mar;37(3):3285-93. doi: 10.1007/s13277-015-4092-9. Epub 2015 Oct 5.
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Semaphorin 4D and hypoxia-inducible factor-1α overexpression is related to prognosis in colorectal carcinoma.信号素4D和缺氧诱导因子-1α的过表达与结直肠癌的预后相关。
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Network pharmacology study and experimental validation of Xiaojianzhong decoction against gastric cancer.小建中汤抗胃癌的网络药理学研究及实验验证
World J Gastrointest Oncol. 2024 Sep 15;16(9):3932-3954. doi: 10.4251/wjgo.v16.i9.3932.
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Deciphering Glioblastoma: Fundamental and Novel Insights into the Biology and Therapeutic Strategies of Gliomas.解读胶质母细胞瘤：对胶质瘤生物学和治疗策略的基础与新见解
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Application progress of liquid biopsy in gastric cancer.液体活检在胃癌中的应用进展
Front Oncol. 2022 Sep 15;12:969866. doi: 10.3389/fonc.2022.969866. eCollection 2022.
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The HIF-1α as a Potent Inducer of the Hallmarks in Gastric Cancer.缺氧诱导因子-1α作为胃癌特征的强效诱导剂。
Cancers (Basel). 2022 May 30;14(11):2711. doi: 10.3390/cancers14112711.
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Therapeutic Targeting Hypoxia-Inducible Factor (HIF-1) in Cancer: Cutting Gordian Knot of Cancer Cell Metabolism.癌症中针对缺氧诱导因子（HIF-1）的治疗靶向：解开癌细胞代谢的戈尔迪之结
Front Genet. 2022 Mar 31;13:849040. doi: 10.3389/fgene.2022.849040. eCollection 2022.
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Loss of RNA binding protein HuD facilitates the production of the senescence-associated secretory phenotype.RNA 结合蛋白 HuD 的缺失促进了衰老相关分泌表型的产生。
Cell Death Dis. 2022 Apr 11;13(4):329. doi: 10.1038/s41419-022-04792-y.
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Uncovering the Mechanisms and Molecular Targets of Weibing Formula 1 against Gastritis: Coupling Network Pharmacology with GEO Database.揭示胃卫兵 1 号治疗胃炎的作用机制及分子靶点：基于网络药理学结合 GEO 数据库分析。
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Role of the CCL2-CCR2 signalling axis in cancer: Mechanisms and therapeutic targeting.CCL2-CCR2 信号轴在癌症中的作用：机制与治疗靶点。
Cell Prolif. 2021 Oct;54(10):e13115. doi: 10.1111/cpr.13115. Epub 2021 Aug 31.
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Is the C-C Motif Ligand 2-C-C Chemokine Receptor 2 Axis a Promising Target for Cancer Therapy and Diagnosis?C-C 基序趋化因子配体 2-C-C 趋化因子受体 2 轴是癌症治疗和诊断的有前途的靶点吗？
Int J Mol Sci. 2020 Dec 7;21(23):9328. doi: 10.3390/ijms21239328.
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The Role of Chemokines in the Development of Gastric Cancer - Diagnostic and Therapeutic Implications.趋化因子在胃癌发展中的作用——诊断和治疗意义。
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本文引用的文献
1
S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages.S100B 通过趋化髓系来源的巨噬细胞促进神经胶质瘤生长。
Clin Cancer Res. 2013 Jul 15;19(14):3764-75. doi: 10.1158/1078-0432.CCR-12-3725. Epub 2013 May 29.
2
Inhibition of CCL2 signaling in combination with docetaxel treatment has profound inhibitory effects on prostate cancer growth in bone.CCL2信号传导的抑制与多西他赛治疗相结合，对骨内前列腺癌的生长具有深远的抑制作用。
Int J Mol Sci. 2013 May 21;14(5):10483-96. doi: 10.3390/ijms140510483.
3
Gastric cancer: epidemiology and risk factors.胃癌：流行病学和危险因素。
Gastroenterol Clin North Am. 2013 Jun;42(2):219-40. doi: 10.1016/j.gtc.2013.01.003. Epub 2013 Mar 29.
4
Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells.基质细胞产生的单核细胞趋化蛋白-1/CCL2 促进 4T1 鼠乳腺癌细胞的肺转移。
PLoS One. 2013;8(3):e58791. doi: 10.1371/journal.pone.0058791. Epub 2013 Mar 18.
5
Relationships of single nucleotide polymorphisms of monocyte chemoattractant protein 1 and chemokine receptor 2 with susceptibility and clinicopathologic characteristics of neoplasia of uterine cervix in Taiwan women.台湾女性中单核细胞趋化蛋白 1 和趋化因子受体 2 的单核苷酸多态性与宫颈癌易感性及临床病理特征的关系。
Reprod Sci. 2013 Oct;20(10):1175-83. doi: 10.1177/1933719113477481. Epub 2013 Feb 20.
6
Hypoxia-mediated regulation of macrophage functions in pathophysiology.缺氧介导的巨噬细胞功能在病理生理学中的调节。
Int Immunol. 2013 Feb;25(2):67-75. doi: 10.1093/intimm/dxs110. Epub 2012 Nov 24.
7
Gastric cancer epidemiology and risk factors.胃癌的流行病学和危险因素。
J Surg Oncol. 2013 Mar;107(3):230-6. doi: 10.1002/jso.23262. Epub 2012 Nov 5.
8
Tumor associated macrophages and neutrophils in tumor progression.肿瘤相关巨噬细胞和中性粒细胞在肿瘤进展中的作用。
J Cell Physiol. 2013 Jul;228(7):1404-12. doi: 10.1002/jcp.24260.
9
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis.CCL2 招募炎症性单核细胞以促进乳腺癌转移。
Nature. 2011 Jun 8;475(7355):222-5. doi: 10.1038/nature10138.
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CCL2 blockade augments cancer immunotherapy.CCL2 阻断增强癌症免疫疗法。
Cancer Res. 2010 Jan 1;70(1):109-18. doi: 10.1158/0008-5472.CAN-09-2326. Epub 2009 Dec 22.
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