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偏头痛与睡眠:新的关联

Migraine and sleep: new connections.

作者信息

Ahn Andrew H, Goadsby Peter J

出版信息

Cerebrum. 2013 Dec 1;2013:15. eCollection 2013 Nov.

Abstract

"Attack" is often a word associated with migraine, and for good reason. If you suffer from migraine headaches or know someone who does, you are well aware of its crippling nature. This story focuses on new research that has uncovered an important link between migraine and sleep patterns. A better understanding of the relationships among the body's circadian rhythms, the brain's hypothalamus, and a mutated gene holds enormous promise of improved care for the more than 36 million Americans who experience migraine (three times more common in women) and the number of people suffering from familial advanced sleep phase syndrome (FASP).

摘要

“发作”通常是一个与偏头痛相关的词汇,这是有充分理由的。如果你患有偏头痛,或者认识患有偏头痛的人,你就会很清楚它那令人致残的特性。本报道聚焦于一项新研究,该研究揭示了偏头痛与睡眠模式之间的重要联系。更好地理解人体昼夜节律、大脑下丘脑和一种突变基因之间的关系,对于改善超过3600万美国人(女性患病率是男性的三倍)的治疗有着巨大的前景,这些美国人患有偏头痛,同时对于患有家族性早睡相位综合征(FASP)的人群也是如此。

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本文引用的文献

2
CGRP and migraine: could PACAP play a role too?降钙素基因相关肽与偏头痛:血管活性肠肽是否也发挥作用?
Neuropeptides. 2013 Dec;47(6):451-61. doi: 10.1016/j.npep.2013.10.010. Epub 2013 Oct 23.
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Migraine prevalence, socioeconomic status, and social causation.偏头痛患病率、社会经济地位与社会致病因素。
Neurology. 2013 Sep 10;81(11):948-55. doi: 10.1212/WNL.0b013e3182a43b32. Epub 2013 Aug 29.
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PLoS One. 2013;8(1):e54074. doi: 10.1371/journal.pone.0054074. Epub 2013 Jan 16.
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Semin Neurol. 2009 Sep;29(4):406-18. doi: 10.1055/s-0029-1237113. Epub 2009 Sep 9.

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