西尼罗河病毒神经侵袭性疾病对静脉注射免疫球蛋白治疗的临床反应。
The clinical response of West Nile virus neuroinvasive disease to intravenous immunoglobulin therapy.
作者信息
Shimoni Zvi, Bin Hanna, Bulvik Shlomo, Niven Mark, Hazzan Rawi, Mendelson Ella, Froom Paul
机构信息
Department of Internal Medicine B, Laniado Hospital, Netanya;
National Center for Zoonotic Viruses, Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical, Tel-Hashomer;
出版信息
Clin Pract. 2012 Jan 27;2(1):e18. doi: 10.4081/cp.2012.e18. eCollection 2012 Jan 1.
Abstract
The aim of the study was to determine whether intravenous gamma globulin (IVIG) treatment is effective in patients with West Nile Virus (WNV) neuroinvasive disease. We contacted hospital based infectious disease experts in Israeli hospitals to identify patients with WNV neuroinvasive disease who were treated with IVIG. The main outcome measure was neurological response after treatment. There were 12 patients who received IVIG and four improved within 48 h. Three patients died, 6 had partial recovery, and 3 recovered completely. Eleven of the 12 patients were infected with Israeli genotypes that are highly homologous to Europe/Africa viruses. The rapid response in some patients suggests that IVIG is effective, and might be used to treat patients with WNV neuroinvasive disease with IVIG.
摘要
该研究的目的是确定静脉注射丙种球蛋白（IVIG）治疗西尼罗河病毒（WNV）神经侵袭性疾病患者是否有效。我们联系了以色列医院中以医院为基础的传染病专家，以确定接受IVIG治疗的WNV神经侵袭性疾病患者。主要结局指标是治疗后的神经反应。有12名患者接受了IVIG治疗，其中4名在48小时内病情有所改善。3名患者死亡，6名部分康复，3名完全康复。12名患者中有11名感染了与欧洲/非洲病毒高度同源的以色列基因型。部分患者的快速反应表明IVIG是有效的，并且可用于治疗WNV神经侵袭性疾病患者。
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本文引用的文献
1
Hyperimmune gammaglobulin for the treatment of West Nile virus encephalitis.用于治疗西尼罗河病毒脑炎的高免疫球蛋白。
Isr Med Assoc J. 2009 Mar;11(3):151-3.
2
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BMC Infect Dis. 2009 Feb 17;9:18. doi: 10.1186/1471-2334-9-18.
3
West Nile virus encephalitis in a renal transplant recipient: the role of intravenous immunoglobulin.一名肾移植受者的西尼罗河病毒脑炎：静脉注射免疫球蛋白的作用
Am J Kidney Dis. 2008 Nov;52(5):e19-21. doi: 10.1053/j.ajkd.2008.03.042. Epub 2008 Aug 3.
4
West Nile virus.西尼罗河病毒
Lancet Neurol. 2007 Feb;6(2):171-81. doi: 10.1016/S1474-4422(07)70030-3.
5
West Nile virus meningoencephalitis.西尼罗河病毒脑膜脑炎
Nat Clin Pract Neurol. 2006 May;2(5):264-75. doi: 10.1038/ncpneuro0176.
6
Acute flaccid paralysis: the spectrum of a newly recognized complication of West Nile virus infection.急性弛缓性麻痹：西尼罗河病毒感染一种新认识的并发症的范围
J Infect. 2005 Aug;51(2):120-7. doi: 10.1016/j.jinf.2004.10.005. Epub 2004 Nov 6.
7
West Nile virus: pathogenesis and therapeutic options.西尼罗河病毒：发病机制与治疗选择
Ann Intern Med. 2004 Apr 6;140(7):545-53. doi: 10.7326/0003-4819-140-7-200404060-00015.
8
The role for intravenous immunoglobulin in the treatment of West Nile virus encephalitis.静脉注射免疫球蛋白在西尼罗河病毒脑炎治疗中的作用。
Clin Infect Dis. 2003 Sep 15;37(6):e88-90. doi: 10.1086/377172. Epub 2003 Aug 27.
9
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Neurology. 2003 Jul 8;61(1):55-9. doi: 10.1212/01.wnl.0000073617.08185.0a.
10
Human immunoglobulin as a treatment for West Nile virus infection.人免疫球蛋白用于治疗西尼罗河病毒感染。
J Infect Dis. 2003 Jul 1;188(1):1-4. doi: 10.1086/376871. Epub 2003 Jun 23.
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