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静脉注射氯胺酮治疗 H1N1 感染诱发的难治性支气管痉挛。

Intravenous Ketamine for Refractory Bronchospasm Precipitated by H1N1 Infection.

机构信息

Department of Pediatrics, Gandhi Medical College and Hamidia Hospital , Bhopal , India.

出版信息

Front Pediatr. 2014 Apr 2;2:24. doi: 10.3389/fped.2014.00024. eCollection 2014.

DOI:10.3389/fped.2014.00024
PMID:24765619
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3980093/
Abstract

Acute severe bronchospasm is an emergency situation and sometimes these children may fail to respond to conventional treatment and deteriorate rapidly to respiratory failure requiring mechanical ventilation. We present a case of 2-year-old girl, who presented with severe bronchospasm resulting in respiratory failure not responding to conventional management including mechanical ventilation and was found to be H1N1 positive. She was treated with ketamine infusion, which led to prompt improvement in airway obstruction.

摘要

急性重度支气管痉挛是一种紧急情况,有时这些儿童可能对常规治疗没有反应,并且迅速恶化至需要机械通气的呼吸衰竭。我们报告了 1 例 2 岁女孩,她因严重支气管痉挛导致呼吸衰竭,对包括机械通气在内的常规治疗无反应,并且被检测出 H1N1 阳性。她接受了氯胺酮输注治疗,这导致气道阻塞迅速改善。

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本文引用的文献

1
Ketamine in status asthmaticus: A review.氯胺酮用于哮喘持续状态:综述
Indian J Crit Care Med. 2013 May;17(3):154-61. doi: 10.4103/0972-5229.117048.
2
Systemic corticosteroids and early administration of antiviral agents for pneumonia with acute wheezing due to influenza A(H1N1)pdm09 in Japan.日本甲型 H1N1 流感病毒导致急性喘息性肺炎患者全身皮质类固醇激素和早期抗病毒药物治疗
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Emergency department use of ketamine in pediatric status asthmaticus.急诊科在小儿哮喘持续状态中使用氯胺酮。
J Asthma. 2001 Dec;38(8):657-64. doi: 10.1081/jas-100107543.
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Status asthmaticus in children: a review.
Chest. 2001 Jun;119(6):1913-29. doi: 10.1378/chest.119.6.1913.