Miller Justin B, Schoenberg Mike R, Bilder Robert M
a Cleveland Clinic , Lou Ruvo Center for Brain Health , Las Vegas , NV , USA.
Clin Neuropsychol. 2014;28(4):575-99. doi: 10.1080/13854046.2014.907445. Epub 2014 Apr 28.
Evidence-based medicine (EBM) is a pillar of clinical medicine (Sackett, Rosenberg, Gray, Haynes, & Richardson, 1996 ), but only recently has this been systematically discussed within the context of clinical neuropsychology (e.g., Chelune, 2010 ). Across the medical sciences, randomized controlled trials (RCTs) are often considered the most important source of evidence for treatment efficacy. To facilitate the conduct, dissemination, and evaluation of research findings, reporting standards have been implemented, including the Consolidated Standards of Reporting Trials (CONSORT) statement. This paper considers the implications of the CONSORT statement for the reporting of clinical trials that include neuropsychological endpoints. Adopting specific guidelines for trials involving neuropsychology endpoints will ultimately serve to strengthen the empirical evidence base by increasing uniformity within the literature, decrease ambiguity in reporting, improving trial design, and fostering methodological transparency. Implementing uniform reporting standards will also facilitate meta-analytic review of evidence from published trials, benefiting researchers, clinicians, educators and practitioners, as well as journal editors, reviewers, and ultimately, health care consumers.
循证医学（EBM）是临床医学的支柱（萨克特、罗森伯格、格雷、海恩斯和理查森，1996年），但直到最近才在临床神经心理学的背景下对此进行系统讨论（例如，切卢内，2010年）。在整个医学领域，随机对照试验（RCT）通常被认为是治疗效果最重要的证据来源。为便于研究结果的开展、传播和评估，已实施报告标准，包括《报告试验的统一标准》（CONSORT）声明。本文探讨了CONSORT声明对包含神经心理学终点的临床试验报告的影响。采用涉及神经心理学终点试验的特定指南最终将通过提高文献的一致性、减少报告中的模糊性、改进试验设计和促进方法透明性来加强实证证据基础。实施统一的报告标准还将促进对已发表试验证据的荟萃分析审查，使研究人员、临床医生、教育工作者和从业者以及期刊编辑、审稿人以及最终的医疗保健消费者受益。
