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[类风湿关节炎和系统性红斑狼疮吸附治疗方法的临床免疫学分析]

[Clinico-immunologic analysis of sorption methods of treatment of rheumatoid arthritis and systemic lupus erythematosus].

作者信息

Venalis A I, Matulis A A, Bareĭkene I P, Mishkinite G A, Tamuliavichene I V

出版信息

Ter Arkh. 1989;61(5):6-10.

PMID:2476866
Abstract

The paper is concerned with the results of the application of the sorption methods for the treatment of patients with rheumatoid arthritis and systemic lupus erythematosus. The authors show the advisability of the use of the above methods for different variants of the disease course, define the time of the treatment and complications common to the sorption methods of the treatment. The results of the treatment by hemoperfusion and enterosorption are compared with the results of the patients' treatment with immunodepressants. A study was made of the action of the sorption methods and immunodepressants on the blood content of the main autoantigens and autoantibodies capable of participation in the forming of the immune complexes. The concentration and the qualitative composition of the circulating immune complexes were studied in the course of the treatment.

摘要

本文关注吸附法治疗类风湿性关节炎和系统性红斑狼疮患者的结果。作者表明了针对疾病不同病程使用上述方法的可取性,确定了治疗时间以及吸附治疗方法常见的并发症。将血液灌流和肠吸附治疗的结果与患者使用免疫抑制剂治疗的结果进行了比较。研究了吸附法和免疫抑制剂对能够参与免疫复合物形成的主要自身抗原和自身抗体血液含量的作用。在治疗过程中研究了循环免疫复合物的浓度和定性组成。

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