Sahil M, Prins C, Kaya G, Poffet F, Boehncke W-H, Cortés B
Rev Med Suisse. 2014 Apr 2;10(424):744, 746-8.
Follicular lymphoma is an indolent B-cell lymphoma. Fluctuant asymptomatic lymphadenopathies are their usual clinical manifestation. B-cell neoplasms can sometimes involve the skin. In this case, it is important to distinguish a systemic B-cell lymphoma with secondary skin involvement from primary cutaneous lymphoma. Immunohistochemical stainings and staging usually allow to make the difference. Here we report the first case of a systemic follicular lymphoma with secondary cutaneous involvement presented with papular lesions on the face mimicking a rosacea.
滤泡性淋巴瘤是一种惰性B细胞淋巴瘤。波动性无症状淋巴结病是其常见临床表现。B细胞肿瘤有时可累及皮肤。在这种情况下,区分伴有继发性皮肤受累的系统性B细胞淋巴瘤与原发性皮肤淋巴瘤很重要。免疫组织化学染色和分期通常有助于做出鉴别。在此,我们报告首例伴有继发性皮肤受累的系统性滤泡性淋巴瘤,表现为面部丘疹性皮损,酷似酒渣鼻。