Rostad Berit, Schmidt Lone, Sundby Johanne, Schei Berit
Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Acta Obstet Gynecol Scand. 2014 Aug;93(8):757-64. doi: 10.1111/aogs.12404. Epub 2014 Jun 4.
Studies suggest that health complaints, distress and poor life satisfaction are associated with infertility experience. Research on health consequences of infertility experience in women has relied heavily on clinic-based samples. This population-based study investigates the association between infertility and health and life satisfaction.
Cross-sectional population-based health study, conducted between 2006 and 2008.
All women in a county in Norway were invited. The current material is restricted to women aged 20-49 years.
A total of 9200 women participated.
Health measures were compared between women with infertility experience (infertile women) and women without infertility experience (non-infertile women). Disparities in health and life satisfaction among the infertile women were assessed.
Self-reported health, functional impairment, depression, anxiety, and life satisfaction.
Some 15.4% of the women had experienced infertility. Infertile women reported poor self-reported health and functional impairment significantly more often than non-infertile women. Childless infertile women had significantly raised adjusted risks for health complaints and dissatisfaction with life compared with non-infertile women with a child, whereas infertile women with a child did not. Differences in health and life satisfaction emerged among the infertile women, but the differences were not significant. There were no significant differences in depression and anxiety between infertile and non-infertile women, or between the two groups of infertile women (with/without a child).
The study confirms the adverse effect of infertility on health and life-satisfaction. The childless infertile women stand out as being vulnerable to the detrimental consequences of infertility.
研究表明，健康问题、痛苦和较低的生活满意度与不孕经历有关。关于女性不孕经历对健康影响的研究严重依赖基于诊所的样本。这项基于人群的研究调查了不孕与健康及生活满意度之间的关联。
2006年至2008年进行的基于人群的横断面健康研究。
挪威一个县的所有女性都被邀请参与。当前的研究对象仅限于20至49岁的女性。
共有9200名女性参与。
比较有不孕经历的女性（不孕女性）和无不孕经历的女性（非不孕女性）的健康指标。评估不孕女性在健康和生活满意度方面的差异。
自我报告的健康状况、功能障碍、抑郁、焦虑和生活满意度。
约15.4%的女性有过不孕经历。不孕女性报告自我感觉健康状况不佳和功能障碍的频率明显高于非不孕女性。与有孩子的非不孕女性相比，无子女的不孕女性出现健康问题和对生活不满的调整后风险显著增加，而有孩子的不孕女性则没有。不孕女性之间在健康和生活满意度上存在差异，但差异不显著。不孕女性与非不孕女性之间，以及两组不孕女性（有/无孩子）之间在抑郁和焦虑方面没有显著差异。
该研究证实了不孕对健康和生活满意度的不利影响。无子女的不孕女性尤其容易受到不孕有害后果的影响。
