Ormerod L D, Abelson M B, Kenyon K R
Eye Research Institute of Retina Foundation, Harvard Medical School, Boston, Massachusetts.
Invest Ophthalmol Vis Sci. 1989 Oct;30(10):2148-53.
Central corneal alkali burn injuries were induced in rabbits by applying five NaOH concentrations on uniformly soaked 7 mm filter paper discs. Clinical parameters were evaluated daily by microscopic examination and photography, and corneal myeloperoxidase levels were measured periodically. Satisfactory alkali burn models of corneal inflammation, vascularization and ulceration were developed by manipulating the alkali concentration.
通过将五种氢氧化钠浓度应用于均匀浸湿的7毫米滤纸圆盘，诱导家兔发生中央角膜碱烧伤。每天通过显微镜检查和摄影评估临床参数，并定期测量角膜髓过氧化物酶水平。通过控制碱浓度，建立了令人满意的角膜炎症、血管化和溃疡的碱烧伤模型。
