Effectiveness of disinfection therapies and promotion of osteoblast growth on osseotite and nanotite implant surfaces.
作者信息
Lubin Judith, Hernandez Maria A, Drukteinis Saulius E, Parker William B, Murray Peter E
机构信息
*Private Practice and Former Resident of Periodontology, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL. †Assistant Professor and Director of Postgraduate Periodontology, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL. ‡Assistant Professor and Director of Predoctoral Periodontology, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL. §Associate Professor and Chair of Periodontology, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL. ‖Professor, Department of Endodontics, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL.
出版信息
Implant Dent. 2014 Aug;23(4):426-33. doi: 10.1097/ID.0000000000000067.
OBJECTIVES
To evaluate the effectiveness of 4 procedures to disinfect implant surfaces intentionally inoculated with bacteria and afterward to evaluate osteoblast viability to the disinfected implant surfaces.
MATERIALS AND METHODS
Eighty-eight commercially pure Osseotite and Nanotite titanium implant discs were inoculated with Porphyromonas gingivalis. The implant surfaces were disinfected with EDTA, tetracycline, citric acid, or neodymium-doped yttrium aluminum garnet (Nd:YAG) laser. The implant discs were then placed in cultures of osteoblast cells.
RESULTS
Osseotite implant discs were easier to disinfect compared with the Nanotite implant discs. Citric acid and tetracycline were the most effective solutions for the disinfection of P. gingivalis from the Osseotite implant discs.
CONCLUSION
The Nanotite implant discs were the most difficult to disinfect, likely because of their chemical and physical properties. Citric acid and tetracycline were most effective for disinfecting the Osseotite implant discs, and further clinical research is needed to verify these effects in vivo. The Nd:YAG laser was the weakest disinfection method, and it is not recommended for disinfecting implant surfaces until its effectiveness is improved.
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