缓解-复发型类比克斯特夫脑炎中的阵发性构音障碍-共济失调

Paroxysmal dysarthria-ataxia in remitting-relapsing Bickerstaff's-like encephalitis.

作者信息

Piffer Silvio, Turri Giulia, Acler Michele, Richelli Silvia, Cerini Roberto, Fiaschi Antonio, Monaco Salvatore, Bonetti Bruno

机构信息

Department of Neurological, Neuropsychological, Morphological and Movement Sciences, Section of Clinical Neurology, University of Verona, Italy.

出版信息

J Neurol Sci. 2014 Jun 15;341(1-2):85-7. doi: 10.1016/j.jns.2014.04.008. Epub 2014 Apr 13.

DOI:10.1016/j.jns.2014.04.008

PMID:24780438

Abstract

Paroxysmal dysarthria-ataxia is a rare neurological condition due to ephaptic transmission, generally appearing in multiple sclerosis patients characterized by stereotyped attacks of slurred speech usually accompanied by ataxia, appearing many times a day. Here we describe a patient with an unusual remitting-relapsing form of Bickerstaff's-like brainstem encephalitis who manifested PDA after a relapse with the involvement of a peculiar region below the red nuclei and benefited from lamotrigine.

摘要

阵发性构音障碍-共济失调是一种由于短路传导导致的罕见神经系统疾病，通常出现在多发性硬化症患者中，其特征为刻板发作的言语含糊，通常伴有共济失调，每天发作多次。在此，我们描述了一名患有不寻常的缓解-复发型类比克斯塔夫脑干脑炎的患者，该患者在复发后累及红核下方一个特殊区域时出现了阵发性构音障碍-共济失调，并从拉莫三嗪治疗中获益。